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Objective <p>This study aimed to evaluate the efficacy of banana leaf extract as a novel antimicrobial coating for surgical sutures, with the primary goal of combating biofilm formation on suture surfaces—the key initiator of Surgical Site Infections (SSIs)—while inhibiting bacterial adhesion and colonization to reduce SSIs and enhance wound healing outcomes.</p> Material and method <p>Fresh banana leaves were processed using Soxhlet extraction to isolate bioactive compounds. Sterile non-absorbable sutures were coated with the extract at varying concentrations and tested against <i>Staphylococcus aureus</i>, <i>Streptococcus mutans</i>, <i>Escherichia coli</i>, Enterococcus <i>faecalis</i> and <i>methicillin-resistant Staphylococcus aureus</i> (MRSA) using agar diffusion and bacterial adhesion assays.</p> Result <p>The banana leaf extract-coated sutures demonstrated significant antibacterial activity against all strains, with zones of inhibition averaging 6.4 ± 1.2&#xa0;mm (<i>S. aureus</i>), 7.1 ± 1.1&#xa0;mm (MRSA), 15.8 ± 1.5&#xa0;mm (<i>S. mutans</i>), 13.6 ± 1.0&#xa0;mm (<i>E. coli</i>), and 14.3 ± 1.3&#xa0;mm (<i>E. faecalis</i>) (<i>p</i> &lt; 0.05 vs. controls by ANOVA/Tukey’s test); <i>S. mutans</i> showed the highest susceptibility. Bacterial adhesion and biofilm formation were significantly reduced on coated sutures compared to uncoated controls (<i>p</i> &lt; 0.05).</p> Conclusion <p>This study concludes that banana leaf extract-coated sutures exhibit broad-spectrum antimicrobial properties, effectively reducing bacterial growth and biofilm formation. This natural coating offers a promising alternative to synthetic antimicrobial agents, addressing concerns over antibiotic resistance and environmental impact.</p>

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Antibacterial effect of banana leaf extract-coated sutures against oral pathogens and MRSA: an in vitro study

  • 期刊论文

  • 发表日期：

    2026年2月18日

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  • Kadambari Vivek Kakde,
  • Deepanjali Megarasu,
  • Manikandhan Ramanathan

摘要

Objective

This study aimed to evaluate the efficacy of banana leaf extract as a novel antimicrobial coating for surgical sutures, with the primary goal of combating biofilm formation on suture surfaces—the key initiator of Surgical Site Infections (SSIs)—while inhibiting bacterial adhesion and colonization to reduce SSIs and enhance wound healing outcomes.

Material and method

Fresh banana leaves were processed using Soxhlet extraction to isolate bioactive compounds. Sterile non-absorbable sutures were coated with the extract at varying concentrations and tested against Staphylococcus aureus, Streptococcus mutans, Escherichia coli, Enterococcus faecalis and methicillin-resistant Staphylococcus aureus (MRSA) using agar diffusion and bacterial adhesion assays.

Result

The banana leaf extract-coated sutures demonstrated significant antibacterial activity against all strains, with zones of inhibition averaging 6.4 ± 1.2 mm (S. aureus), 7.1 ± 1.1 mm (MRSA), 15.8 ± 1.5 mm (S. mutans), 13.6 ± 1.0 mm (E. coli), and 14.3 ± 1.3 mm (E. faecalis) (p < 0.05 vs. controls by ANOVA/Tukey’s test); S. mutans showed the highest susceptibility. Bacterial adhesion and biofilm formation were significantly reduced on coated sutures compared to uncoated controls (p < 0.05).

Conclusion

This study concludes that banana leaf extract-coated sutures exhibit broad-spectrum antimicrobial properties, effectively reducing bacterial growth and biofilm formation. This natural coating offers a promising alternative to synthetic antimicrobial agents, addressing concerns over antibiotic resistance and environmental impact.