Objectives <p>Evaluation of the effectiveness Gengigel^® Oral Gel (hyaluronic acid ) and photobiomodulation (magnetic laser) in the treatment of alveolar osteitis in patients with type 2 diabetes mellitus.</p> Methods <p>This is a blind RCT study clinical prospective study in 69 patients with type 2 diabetes mellitus with alveolar osteitis. The subjects selected for study were examined under the inclusion and exclusion criteria and sign the written consent. The patients were blind randomly assigned into two groups: The Group I included 35 patients with alveolar osteitis, in which complex treatment including HA and magnetic laser therapy was carried out. The Group II is represented by 34 patients, with alveolar osteitis received treatment including antiseptic and inflammatory agents. Healing time and pain levels of the alveolar socket of the extracted tooth were appreciated. The pain levels in dynamics were assessed according to VAS.</p> Results <p>After the 5th treatment session, 91% of patients in the 1st group had a VAS score of 0 (no pain), whereas in 9% of patients, the VAS score was 1–3. In group 2, a similar result of the VAS score was recorded but only on the 8th day of treatment.</p> Conclusion <p>The results show that the use of Gengigel^® Oral Gel (hyaluronic acid ) and photobiomodulation(magnetic laser) recommended for the treatment of dry socket in patients with type 2 diabetes mellitus, can be considered as a promising method, as it has not only anti-inflammatory but also pronounced analgesic and tissue regenerating properties.</p> Clinical trial number <p>Not applicable.</p>