Scholarlink

Objectives <p>The global prevalence of childhood obesity has surged in recent years. Children who are overweight or obese frequently exhibit accelerated dental development, skeletal maturation, and earlier onset of puberty. This study explores the relationship between insulin resistance and the advancement of dental and skeletal maturation in growing individuals. Additionally, it evaluates wrist circumference—an easily measurable clinical marker associated with insulin resistance—as a potential independent predictor of dental advancement in orthodontic patients.</p> Materials and methods <p>Assessed parameters included chronological age (7–14 years), anthropometric measurements (weight, height, body mass index [BMI], waist and wrist circumference, waist-to-height ratio [WHtR]), glucose profile, insulin resistance markers, cervical vertebrae maturation stage (CVMS), and dental age advancement (calculated as dental age minus chronological age). Eighteen patients were stratified into three BMI-based groups: normal-weight subjects, patients who are overweight, and patients who are obese.</p> Results <p>Statistical analysis showed a strong association between BMI and dental age advancement. Wrist circumference and WHtR were stronger and more reliable predictors of skeletal maturation than BMI. Insulin resistance was significantly correlated with dental age advancement, emphasizing the influence of metabolic health on dental development. Multivariate analysis identified wrist circumference and WHtR as key predictors of dental age advancement.</p> Conclusions <p>This pilot study suggests a potential association between BMI, insulin resistance, anthropometric measures, and the advancement of dental and skeletal maturation in children who are overweight or obese. These preliminary findings highlight the possible influence of metabolic health on growth patterns.</p> Clinical relevance <p>Considering metabolic indicators such as wrist circumference and waist-to-height ratio in growing patients may help orthodontists identify those at risk of accelerated dental development and optimize the timing of individualized treatment.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Exploring the relationship between insulin resistance, wrist circumference, dental age, and skeletal maturation in growing patients with overweight and obesity: a pilot study

  • 期刊论文

  • 发表日期：

    2026年3月26日

查看全文
  • Camilla Grenga,
  • Rosanna Guarnieri,
  • Roberto Di Giorgio,
  • Gabriele Veroi,
  • Mariaignazia Curreli,
  • Davide Masi,
  • Carla Lubrano,
  • Ersilia Barbato

摘要

Objectives

The global prevalence of childhood obesity has surged in recent years. Children who are overweight or obese frequently exhibit accelerated dental development, skeletal maturation, and earlier onset of puberty. This study explores the relationship between insulin resistance and the advancement of dental and skeletal maturation in growing individuals. Additionally, it evaluates wrist circumference—an easily measurable clinical marker associated with insulin resistance—as a potential independent predictor of dental advancement in orthodontic patients.

Materials and methods

Assessed parameters included chronological age (7–14 years), anthropometric measurements (weight, height, body mass index [BMI], waist and wrist circumference, waist-to-height ratio [WHtR]), glucose profile, insulin resistance markers, cervical vertebrae maturation stage (CVMS), and dental age advancement (calculated as dental age minus chronological age). Eighteen patients were stratified into three BMI-based groups: normal-weight subjects, patients who are overweight, and patients who are obese.

Results

Statistical analysis showed a strong association between BMI and dental age advancement. Wrist circumference and WHtR were stronger and more reliable predictors of skeletal maturation than BMI. Insulin resistance was significantly correlated with dental age advancement, emphasizing the influence of metabolic health on dental development. Multivariate analysis identified wrist circumference and WHtR as key predictors of dental age advancement.

Conclusions

This pilot study suggests a potential association between BMI, insulin resistance, anthropometric measures, and the advancement of dental and skeletal maturation in children who are overweight or obese. These preliminary findings highlight the possible influence of metabolic health on growth patterns.

Clinical relevance

Considering metabolic indicators such as wrist circumference and waist-to-height ratio in growing patients may help orthodontists identify those at risk of accelerated dental development and optimize the timing of individualized treatment.

Graphical abstract