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Objective <p>This randomized clinical trial evaluated a copaiba oil-based gel in controlling dental sensitivity (DS) and color change after dental bleaching.</p> Materials and methods <p>Seventy-five volunteers were randomized into three groups (<i>n</i> = 25): GC (placebo gel – negative control); GKF2% (gel of 5% potassium nitrate and 2% sodium fluoride – positive control); and GCO (copaiba oil gel). Three bleaching sessions were performed using 35% hydrogen peroxide (HP 35%), with 7-day intervals. The desensitizing gels were applied for 10&#xa0;min in each group. The DS was evaluated over 21&#xa0;days using a visual analog scale (VAS). Color evaluation was done with a spectrophotometer before and after bleaching using the CIEDE2000. The DS was assessed between groups (Kruskal–Wallis test) and within groups (Friedman test). The color change was analyzed using one-way ANOVA and Tukey's test.</p> Results <p>GCO and GKF2% showed the lowest sensitivity values, with no significant difference (<i>p</i> &lt; 0.05). In the intragroup analysis, GCO and GKF2% showed no differences across the three whitening sessions (<i>p</i> = 0.974, <i>p</i> = 0.213, <i>p</i> = 0.143, respectively). Conversely, GC exhibited an increase in DS after the last session (<i>p</i> = 0.035). All groups showed color change, without statistically significant differences between the groups (<i>p</i> = 0.725).</p> Conclusion <p>The copaiba gel reduced dental sensitivity after treatment with 35% hydrogen peroxide, without affecting the bleaching effectiveness.</p> Clinical relevance <p>The topical application of the experimental copaiba oil gel was effective in reducing dental sensitivity after bleaching with 35% hydrogen peroxide.</p>

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Effect of copaiba oil-resin on dental sensitivity control and color change after bleaching: A randomized clinical trial

  • 期刊论文

  • 发表日期：

    2025年5月13日

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  • Giovana Solheid Gil,
  • Gabriela Monteiro Barbosa Xavier,
  • Caio Augusto de Almeida Canelas,
  • Rafael Rodrigues Lima,
  • Ana Paula Drummond Rodrigues,
  • Jesuina Lamartine Nogueira Araújo,
  • Marcele Fonseca Passos,
  • Cecy Martins Silva

摘要

Objective

This randomized clinical trial evaluated a copaiba oil-based gel in controlling dental sensitivity (DS) and color change after dental bleaching.

Materials and methods

Seventy-five volunteers were randomized into three groups (n = 25): GC (placebo gel – negative control); GKF2% (gel of 5% potassium nitrate and 2% sodium fluoride – positive control); and GCO (copaiba oil gel). Three bleaching sessions were performed using 35% hydrogen peroxide (HP 35%), with 7-day intervals. The desensitizing gels were applied for 10 min in each group. The DS was evaluated over 21 days using a visual analog scale (VAS). Color evaluation was done with a spectrophotometer before and after bleaching using the CIEDE2000. The DS was assessed between groups (Kruskal–Wallis test) and within groups (Friedman test). The color change was analyzed using one-way ANOVA and Tukey's test.

Results

GCO and GKF2% showed the lowest sensitivity values, with no significant difference (p < 0.05). In the intragroup analysis, GCO and GKF2% showed no differences across the three whitening sessions (p = 0.974, p = 0.213, p = 0.143, respectively). Conversely, GC exhibited an increase in DS after the last session (p = 0.035). All groups showed color change, without statistically significant differences between the groups (p = 0.725).

Conclusion

The copaiba gel reduced dental sensitivity after treatment with 35% hydrogen peroxide, without affecting the bleaching effectiveness.

Clinical relevance

The topical application of the experimental copaiba oil gel was effective in reducing dental sensitivity after bleaching with 35% hydrogen peroxide.