Scholarlink

Objective <p>The study evaluated the longevity, efficacy, sensitivity, and impact on the oral health-related quality of life of in-office dental bleaching using low, medium, and high concentrate hydrogen peroxide.</p> Material and Methods <p>Randomized, parallel, and double-blinded clinical trial was performed with 54 participants using18% hydrogen peroxide (HP), 25%HP, and 40%HP in-office bleaching agent. Tooth color was evaluated at baseline, after the 1st session bleaching, after the 2nd session bleaching and 6 months after finishing the bleaching using spectrophotometer. Tooth sensitivity (TS) was measured with the Visual Analog Scale at baseline, immediately after bleaching, after 1 day, and after 7 days. The impact on quality of life was evaluated using the 14-item Oral Health Impact Profile (OHIP-14) questionnaire at baseline, and 6 months after bleaching. The data were analyzed using the Kikare test, Kruskal Wallis test, one-way ANOVA, Wilcoxon, Friedman, Mann–Whitney (<i>p</i> &lt; 0.05).</p> Results <p>All groups achieved similar levels of bleaching during all evaluation times (<i>p</i> &gt; 0.05), surpassing perceived value. There was no difference in TS levels among groups at all evaluation times (<i>p</i> &gt; 0.05). TS significantly increased after bleaching (<i>p</i> &lt; 0.05), decreased significantly after 24&#xa0;h (<i>p</i> &lt; 0.05), and there was no difference no difference between the initial sensitivity levels after 7&#xa0;days (<i>p</i> &gt; 0.05). All groups reported improved aesthetic self-perception following bleaching (<i>p</i> &lt; 0.05) and there was no difference between the groups (<i>p</i> &gt; 0.05).</p> Conclusion <p>Low, medium, and high concentrations of HP did not affect both the final tooth color and the reported TS intensity, regardless of the evaluation time. In-office bleaching provides positive effects on aesthetic perception and different HP concentrations have not influenced this positive effect.</p> Clinical significance <p>In this study, the efficacy, longevity, sensitivity, and impact on oral health-related quality of life of in-office bleaching using low, medium, and high concentration hydrogen peroxide agents from the same manufacturer were found to be similar. However, these results cannot be extrapolated to other in-office high-concentration hydrogen peroxide gels.</p> Clinical trial registration number <p>NCT06700434.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Clinical evaluation of in-office bleaching with low, medium, and high concentrate hydrogen peroxide: a 6-month a double-blinded randomized controlled trial

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年4月21日

查看全文
  • Hanife Altınışık,
  • Merve Nezir

摘要

Objective

The study evaluated the longevity, efficacy, sensitivity, and impact on the oral health-related quality of life of in-office dental bleaching using low, medium, and high concentrate hydrogen peroxide.

Material and Methods

Randomized, parallel, and double-blinded clinical trial was performed with 54 participants using18% hydrogen peroxide (HP), 25%HP, and 40%HP in-office bleaching agent. Tooth color was evaluated at baseline, after the 1st session bleaching, after the 2nd session bleaching and 6 months after finishing the bleaching using spectrophotometer. Tooth sensitivity (TS) was measured with the Visual Analog Scale at baseline, immediately after bleaching, after 1 day, and after 7 days. The impact on quality of life was evaluated using the 14-item Oral Health Impact Profile (OHIP-14) questionnaire at baseline, and 6 months after bleaching. The data were analyzed using the Kikare test, Kruskal Wallis test, one-way ANOVA, Wilcoxon, Friedman, Mann–Whitney (p < 0.05).

Results

All groups achieved similar levels of bleaching during all evaluation times (p > 0.05), surpassing perceived value. There was no difference in TS levels among groups at all evaluation times (p > 0.05). TS significantly increased after bleaching (p < 0.05), decreased significantly after 24 h (p < 0.05), and there was no difference no difference between the initial sensitivity levels after 7 days (p > 0.05). All groups reported improved aesthetic self-perception following bleaching (p < 0.05) and there was no difference between the groups (p > 0.05).

Conclusion

Low, medium, and high concentrations of HP did not affect both the final tooth color and the reported TS intensity, regardless of the evaluation time. In-office bleaching provides positive effects on aesthetic perception and different HP concentrations have not influenced this positive effect.

Clinical significance

In this study, the efficacy, longevity, sensitivity, and impact on oral health-related quality of life of in-office bleaching using low, medium, and high concentration hydrogen peroxide agents from the same manufacturer were found to be similar. However, these results cannot be extrapolated to other in-office high-concentration hydrogen peroxide gels.

Clinical trial registration number

NCT06700434.