Efficacy of preoperative and postoperative medications in reducing pain after non-surgical root canal treatment: an umbrella review

期刊论文
发表日期：

2024年8月14日

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Felipe de Souza Matos,
Laura Elias Rocha,
Mateus da Costa Lima,
Márcia Valente de Brito Dantas,
Rômulo Dias Jesuino,
João Marcos da Costa Ribeiro,
Walbert de Andrade Vieira,
Luiz Renato Paranhos

摘要

Objective

This study analyzed, using an umbrella review, existing systematic reviews on medications to prevent and control postoperative endodontic pain to guide professionals in choosing the most effective drug.

Materials and methods

An electronic search in the PubMed (MEDLINE), LILACS, SciELO, EMBASE, Scopus, Web of Science, Cochrane Reviews, and Data Archiving and Networked Services (DANS) databases retrieved 17 systematic reviews. The study included only systematic reviews of clinical trials with or without meta-analyses evaluating effectiveness of medications in reducing pain after non-surgical endodontic treatment.

Results

The evidence showed that steroidal and non-steroidal anti-inflammatory drugs and opioids effectively controlled pain within six to 24 h.

Conclusions

Dexamethasone, prednisolone, paracetamol, and mainly ibuprofen provided higher postoperative pain relief. The quality of evidence of the reviews ranged from very low to high, and the risk of bias from low to high, suggesting the need for well-designed clinical trials to provide confirmatory evidence.

Clinical relevance

This review emphasizes the efficacy of developing protocols for pain control after endodontic therapy.