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<p>In women the prevalence of all three major vascular surgical diseases, i.e., peripheral arterial occlusive disease (PAOD), carotid artery stenosis and aortic diseases, is lower than in men but increases with age due to postmenopausal hormonal changes and the reduced vasoprotective effect of estrogen. There are also gender-specific differences with respect to the typical symptoms of PAOD and aortic diseases. Women more frequently present with long-term asymptomatic progression or atypical symptoms, which can lead to a&#xa0;delayed diagnosis. In carotid artery stenosis, gender-specific anatomy, smaller vessel diameters and different plaque formations necessitate gender-specific treatment decisions. Also, the use of standard vascular grafts in women can be limited in open surgical and endovascular procedures because of their specific anatomy, which potentially affects the outcome.</p>

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Gefäßpatientinnen – genderspezifische Symptome, Diagnostik und Therapie

  • 期刊论文

  • 发表日期：

    2026年1月12日

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  • Deborah Uebermuth,
  • Amelie Behrens,
  • Patricia Ettler

摘要

In women the prevalence of all three major vascular surgical diseases, i.e., peripheral arterial occlusive disease (PAOD), carotid artery stenosis and aortic diseases, is lower than in men but increases with age due to postmenopausal hormonal changes and the reduced vasoprotective effect of estrogen. There are also gender-specific differences with respect to the typical symptoms of PAOD and aortic diseases. Women more frequently present with long-term asymptomatic progression or atypical symptoms, which can lead to a delayed diagnosis. In carotid artery stenosis, gender-specific anatomy, smaller vessel diameters and different plaque formations necessitate gender-specific treatment decisions. Also, the use of standard vascular grafts in women can be limited in open surgical and endovascular procedures because of their specific anatomy, which potentially affects the outcome.