Background <p>In Germany alone, over 13,000 procedures are performed annually for abdominal aortic aneurysms (AAAs). Of these, almost 18% are already symptomatic or have even ruptured. As the main risk factors for developing an AAA are age, high blood pressure, gender, and smoking, it must be assumed that, with an ageing population, AAAs will continue to be considered a&#xa0;relevant disease of old age in the future. This results in a&#xa0;need for meaningful imaging modalities and evaluation algorithms for screening, surveillance, and surgical or interventional planning for AAAs. By means of photon-counting computed tomography (PCCT) and radiomics analyses new possibilities open up for risk stratification and therapy planning.</p> Objectives <p>This study offers an overview of the current status of research on CT imaging of AAAs, as well as on its use for surveillance and treatment planning, with special focus on PCCT and radiomics.</p> Methods <p>To conduct this study, a&#xa0;systematic literature search of the online databases PubMed and Google Scholar was performed.</p> Results <p>The currently established imaging biomarkers are suitable for a&#xa0;proper risk assessment, but they can sometimes only evaluate the risk of rupture in an unsatisfactory manner. The improved imaging quality of PCCT offers new possibilities for more accurate measurement of existing biomarkers, as well as the analysis of image features with radiomics whereby new imaging biomarkers can be discovered.</p> Conclusions <p>In cardiac imaging radiomics analyses of PCCT datasets show promising results. However, studies on radiomics in AAAs are sparse, highlighting the need for further clinical research.</p>

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Innovationen in der vaskulären Bildgebung durch die Photon-Counter-CT-Technologie

  • Isabelle Ayx,
  • Mimi D. Rademacher,
  • Stefan O. Schoenberg,
  • Christoph Reißfelder,
  • Kay Schwenke

摘要

Background

In Germany alone, over 13,000 procedures are performed annually for abdominal aortic aneurysms (AAAs). Of these, almost 18% are already symptomatic or have even ruptured. As the main risk factors for developing an AAA are age, high blood pressure, gender, and smoking, it must be assumed that, with an ageing population, AAAs will continue to be considered a relevant disease of old age in the future. This results in a need for meaningful imaging modalities and evaluation algorithms for screening, surveillance, and surgical or interventional planning for AAAs. By means of photon-counting computed tomography (PCCT) and radiomics analyses new possibilities open up for risk stratification and therapy planning.

Objectives

This study offers an overview of the current status of research on CT imaging of AAAs, as well as on its use for surveillance and treatment planning, with special focus on PCCT and radiomics.

Methods

To conduct this study, a systematic literature search of the online databases PubMed and Google Scholar was performed.

Results

The currently established imaging biomarkers are suitable for a proper risk assessment, but they can sometimes only evaluate the risk of rupture in an unsatisfactory manner. The improved imaging quality of PCCT offers new possibilities for more accurate measurement of existing biomarkers, as well as the analysis of image features with radiomics whereby new imaging biomarkers can be discovered.

Conclusions

In cardiac imaging radiomics analyses of PCCT datasets show promising results. However, studies on radiomics in AAAs are sparse, highlighting the need for further clinical research.