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<p>Lipid metabolism disorders and diabetes mellitus are interrelated and increase the cardiovascular risk. Insulin resistance, dyslipidemia and genetic factors play a&#xa0;key role in this interaction. Impaired lipid processing leads to altered triglyceride, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) levels, which increase the risk of atherosclerosis and cardiovascular events. A&#xa0;healthy diet, weight reduction and regular exercise are decisive. Medications, such as metformin, statins, and glucagon-like peptide 1 (GLP-1) agonists as well as combination therapy, can improve insulin sensitivity, regulate lipid metabolism and reduce the cardiovascular risk, particularly for diabetics with a high risk of cardiovascular diseases.</p>

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Interaktion von Fettstoffwechselstörungen und Diabetes mellitus: Therapeutische Implikation

  • 期刊论文

  • 发表日期：

    2025年4月29日

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  • I. Baumgartner

摘要

Lipid metabolism disorders and diabetes mellitus are interrelated and increase the cardiovascular risk. Insulin resistance, dyslipidemia and genetic factors play a key role in this interaction. Impaired lipid processing leads to altered triglyceride, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) levels, which increase the risk of atherosclerosis and cardiovascular events. A healthy diet, weight reduction and regular exercise are decisive. Medications, such as metformin, statins, and glucagon-like peptide 1 (GLP-1) agonists as well as combination therapy, can improve insulin sensitivity, regulate lipid metabolism and reduce the cardiovascular risk, particularly for diabetics with a high risk of cardiovascular diseases.