<p>In Germany, there are around 15&#xa0;million parents with underage children, of whom around 37,000 are newly diagnosed with cancer every year. Breast cancer is by far the most common tumor site for all new cancer cases in women. If parents are middle aged when diagnosed, they are faced with a&#xa0;number of challenges such as the physical illness itself, concerns about mortality, and questions of meaning. In addition to these illness-related issues, parents in this age group must navigate areas of life, e.g., planning and starting a&#xa0;family, marriage/partnership, work, or career. Patients with underage children also face additional organizational and emotional burden. These include their own physical and mental capacities, the organization of childcare, and also the question of how to communicate their illness with their children. Children experience changes as a&#xa0;result of their parents’ illness and have different resources to cope with the situation. They are at an elevated risk of developing emotional or behavioral problems, for example, by postponing their own needs. Without an explanation for the changes in their life, children attempt to find their own answers. Therefore, it is crucial to inform them about the illness as early as possible and in an age-appropriate way so that they can orientate themselves cognitively and develop coping strategies. It is recommended that healthcare professionals provide psycho-oncological support to affected families. Proactive communication about the patient’s family issues, knowledge of regional support services for families, and about the impact of the disease on children will help to identify and address the needs of affected families. A&#xa0;free e‑learning program for healthcare professionals is available to raise awareness and provide basic knowledge.</p>