<p>This paper investigates the transient fracture behaviors of an interface crack in a magnetoelectric sandwich structure subjected to an electric impact loading. The sandwich structure consists of a middle piezomagnetic layer with arbitrary magnetized direction and two outer piezoelectric layers with arbitrary poling direction. By applying Laplace and Fourier transform, the mixed boundary value problem is reduced to a standard Cauchy singular integral equation of the second kind, which is solved numerically to obtain the dynamic field intensity factors near the crack tip. The results reveal that the effects of polarization orientation and constitutive parameters on fracture behavior strongly depend on the role each phase plays in the magnetoelectric transduction process: The polarization orientation of the active layers primarily controls the fracture mode, while stiffer active layers combined with softer passive layers enhance interfacial compatibility and fracture resistance. These findings provide valuable theoretical insights for optimizing the performance and ensuring the long-term reliability of magnetoelectric devices.</p>