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<p>The functionalized pyrazole derivatives are produced from the reaction of hydrazonoyl chloride with ethyl 3-oxo-3-phenylpropanoate, acetylacetone, ethyl cyanoacetate, methyl cyanoacetate, or malononitrile in the presence of inexpensive sodium methoxide as base in DMF under catalyst-free condition in 78–90% yields.</p> Graphical abstract <p></p>

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An efficient reaction for the synthesis of functionalized pyrazoles

  • 期刊论文

  • 发表日期：

    2025年11月10日

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  • Azam Mansournejad,
  • Gholamhossein Khalili

摘要

The functionalized pyrazole derivatives are produced from the reaction of hydrazonoyl chloride with ethyl 3-oxo-3-phenylpropanoate, acetylacetone, ethyl cyanoacetate, methyl cyanoacetate, or malononitrile in the presence of inexpensive sodium methoxide as base in DMF under catalyst-free condition in 78–90% yields.

Graphical abstract