<p>Feline leukaemia virus subgroup A (FeLV-A) is transmitted among cats, and FeLV subgroups are frequently generated <i>de novo</i>. We investigated the frequency of detection of subgroups using interference assays in 50 cases. FeLV-A infection alone was detected in 38% of the cases, whereas coinfection with both FeLV-A and FeLV-B was observed in 62% of the cases. No cases of FeLV-B infection alone were observed. Cases of coinfection with FeLV-A and FeLV-B showed a higher prevalence than cases of FeLV-A infection alone. The FeLV containing an X region was discovered in two new cases. This study may help to elucidate the mechanism underlying FeLV-B-associated diseases.</p>

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Feline leukaemia virus subgrouping using a viral interference assay

  • Dimas Arya Abdillah,
  • Takahiro Hiratsuka,
  • Fumiko Matsuyama,
  • Yuki Hattori,
  • Takehisa Soma,
  • Tetsuya Shimoda,
  • Takashi Kato,
  • Hideo Sakai,
  • Masaharu Hisasue,
  • Ariko Miyake,
  • Kazuo Nishigaki

摘要

Feline leukaemia virus subgroup A (FeLV-A) is transmitted among cats, and FeLV subgroups are frequently generated de novo. We investigated the frequency of detection of subgroups using interference assays in 50 cases. FeLV-A infection alone was detected in 38% of the cases, whereas coinfection with both FeLV-A and FeLV-B was observed in 62% of the cases. No cases of FeLV-B infection alone were observed. Cases of coinfection with FeLV-A and FeLV-B showed a higher prevalence than cases of FeLV-A infection alone. The FeLV containing an X region was discovered in two new cases. This study may help to elucidate the mechanism underlying FeLV-B-associated diseases.