Scholarlink

<p>Oyster hatcheries suffer significant mortality caused by members of the bacterial genus <i>Vibrio</i>, which infect <i>Crassostrea gigas</i> larvae. Bacteriophages present a potential alternative to antibiotics, with N4-like phages showing promise against vibriosis. We investigated the adsorption properties and determined the complete genome sequence of phage pVco-7 and performed phylogenetic and comparative analysis with other N4-like <i>Vibrio</i> phages to gain insights into phage resistance mechanisms and infection strategies. The phage has a linear dsDNA genome with 126 genes and a typical N4-like organization. Tail fiber variations were identified that could potentially influence host recognition, providing insights into how phages of the genus <i>Vicoquintavirus</i> interact with their host as well as their evolutionary relationships. These findings will contribute to the development effective biocontrol strategies against vibriosis in commercially important bivalve aquaculture.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Comparison of the genomes of Vibrio phages pVco-5 and pVco-7: implications for phage-host interactions

  • 期刊论文

  • 发表日期：

    2025年8月27日

查看全文
  • Hyoun Joong Kim,
  • Jun Kwon,
  • Chan Hee Lee,
  • Ji Hyung Kim,
  • Se Chang Park,
  • Sang Guen Kim

摘要

Oyster hatcheries suffer significant mortality caused by members of the bacterial genus Vibrio, which infect Crassostrea gigas larvae. Bacteriophages present a potential alternative to antibiotics, with N4-like phages showing promise against vibriosis. We investigated the adsorption properties and determined the complete genome sequence of phage pVco-7 and performed phylogenetic and comparative analysis with other N4-like Vibrio phages to gain insights into phage resistance mechanisms and infection strategies. The phage has a linear dsDNA genome with 126 genes and a typical N4-like organization. Tail fiber variations were identified that could potentially influence host recognition, providing insights into how phages of the genus Vicoquintavirus interact with their host as well as their evolutionary relationships. These findings will contribute to the development effective biocontrol strategies against vibriosis in commercially important bivalve aquaculture.