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Background <p>Neurosurgical patients frequently require intensive postoperative care. However, data on the factors influencing their outcomes in low-resource environments are limited. This study aimed to identify the predictors of mortality among neurosurgical patients admitted to the Surgical Intensive Care Unit at the Tikur Anbessa Specialized Hospital, Ethiopia.</p> Methods <p>A retrospective cohort study was conducted between January 1, 2024, and January 1, 2025. All neurosurgical patients admitted to the surgical Intensive Care during the study period were reviewed. Patient outcomes were categorized as death during Intensive Care Unit stay or discharge or transfer with clinical improvement. Multivariate logistic regression analysis was performed using SPSS version 27, and variables with <i>p</i> &lt; 0.05 were considered statistically significant.</p> Results <p>A total of 140 neurosurgical patients were included, with an overall ICU mortality rate of 23% (<i>n</i> = 32). Emergency surgery (AOR = 7.4; 95% CI: 1.26–13.97; <i>p</i> = 0.027), intraoperative blood loss &gt; 1000&#xa0;mL (AOR = 4.0; 95% CI: 1.96–5.29; <i>p</i> = 0.044), lack of continuous postoperative monitoring (AOR = 3.5; 95% CI: 1.93–13.15; <i>p </i>= 0.044), and ICU complications (AOR = 7.8; 95% CI: 1.92–13.49; <i>p</i> = 0.004) were independently associated with increased mortality.</p> Conclusion <p>23% Of the neurosurgical patients admitted to the SICU died during the ICU stay. Mortality was independently associated with emergency surgery, significant intraoperative blood loss, lack of continuous postoperative monitoring, and the occurrence of ICU-related complications.</p>

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Mortality and its predictors among neurosurgical patients admitted to the surgical ICU in a resource-limited setting: experience from Ethiopia

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月24日

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  • Absera Gebriel Yohannes,
  • Molla Asnake Kebede,
  • Amira Shamil,
  • Kidus Geabriel Yohannes,
  • Dejen Tekiea Gebrewahd,
  • Turi Abateka Abadiga,
  • Abera Kuma,
  • Selemon Gebrezgabiher Asgedom

摘要

Background

Neurosurgical patients frequently require intensive postoperative care. However, data on the factors influencing their outcomes in low-resource environments are limited. This study aimed to identify the predictors of mortality among neurosurgical patients admitted to the Surgical Intensive Care Unit at the Tikur Anbessa Specialized Hospital, Ethiopia.

Methods

A retrospective cohort study was conducted between January 1, 2024, and January 1, 2025. All neurosurgical patients admitted to the surgical Intensive Care during the study period were reviewed. Patient outcomes were categorized as death during Intensive Care Unit stay or discharge or transfer with clinical improvement. Multivariate logistic regression analysis was performed using SPSS version 27, and variables with p < 0.05 were considered statistically significant.

Results

A total of 140 neurosurgical patients were included, with an overall ICU mortality rate of 23% (n = 32). Emergency surgery (AOR = 7.4; 95% CI: 1.26–13.97; p = 0.027), intraoperative blood loss > 1000 mL (AOR = 4.0; 95% CI: 1.96–5.29; p = 0.044), lack of continuous postoperative monitoring (AOR = 3.5; 95% CI: 1.93–13.15; p = 0.044), and ICU complications (AOR = 7.8; 95% CI: 1.92–13.49; p = 0.004) were independently associated with increased mortality.

Conclusion

23% Of the neurosurgical patients admitted to the SICU died during the ICU stay. Mortality was independently associated with emergency surgery, significant intraoperative blood loss, lack of continuous postoperative monitoring, and the occurrence of ICU-related complications.