Scholarlink

Background <p>Idiopathic normal pressure hydrocephalus (iNPH) is a neurological disease characterized by ventriculomegaly and Hakim’s triad. At present, symptoms can be alleviated only by cerebrospinal fluid (CSF) shunt surgery. Yet, various complications after shunting may occur, occasionally requiring repeated shunt revisions. In this retrospective, population-based study, our objective was to compare revision rates and causes for revision surgeries between adjustable shunt valve and fixed-pressure valves in iNPH patients.</p> Methods <p>Altogether 1220 patients were evaluated for possible iNPH at Kuopio University Hospital between 1991 and 2023. Probable iNPH was diagnosed in 809 patients who received their first ventriculoperitoneal shunt (VPS). Of the patient cohort, 566 were shunted using an adjustable valve (2008–2023) and 243 received a fixed pressure valve (1991–2012). Hospital records and nationwide registries were used to construct a timeline for each patient from the shunt insertion and until death (<i>n</i> = 430) or the end of 2023.</p> Results <p>Overall revision rate was lower in iNPH patients receiving an adjustable valve (14% vs. 30%, <i>p</i> &lt; .001, 95% CI 0.27—0.56). The incidence of multiple revisions was also lower in the adjustable valve group (27% vs. 32% <i>p</i> = 0.002, 95% CI 0.21—0.71). The most common cause for revision was peritoneal catheter malposition in the adjustable valve group (44%) and shunt underdrainage in the fixed-pressure valve group (25%).</p> Conclusions <p>Adjustable shunt valves have decreased the need for shunt revision surgeries due to under- and overdrainage.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Reduced risk of shunt revision with adjustable valves: a population-based cohort study over three decades

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月3日

查看全文
  • Siiri Oksa,
  • Roosa Kasurinen,
  • Anssi Lipponen,
  • Ville Leinonen,
  • Antti J. Luikku

摘要

Background

Idiopathic normal pressure hydrocephalus (iNPH) is a neurological disease characterized by ventriculomegaly and Hakim’s triad. At present, symptoms can be alleviated only by cerebrospinal fluid (CSF) shunt surgery. Yet, various complications after shunting may occur, occasionally requiring repeated shunt revisions. In this retrospective, population-based study, our objective was to compare revision rates and causes for revision surgeries between adjustable shunt valve and fixed-pressure valves in iNPH patients.

Methods

Altogether 1220 patients were evaluated for possible iNPH at Kuopio University Hospital between 1991 and 2023. Probable iNPH was diagnosed in 809 patients who received their first ventriculoperitoneal shunt (VPS). Of the patient cohort, 566 were shunted using an adjustable valve (2008–2023) and 243 received a fixed pressure valve (1991–2012). Hospital records and nationwide registries were used to construct a timeline for each patient from the shunt insertion and until death (n = 430) or the end of 2023.

Results

Overall revision rate was lower in iNPH patients receiving an adjustable valve (14% vs. 30%, p < .001, 95% CI 0.27—0.56). The incidence of multiple revisions was also lower in the adjustable valve group (27% vs. 32% p = 0.002, 95% CI 0.21—0.71). The most common cause for revision was peritoneal catheter malposition in the adjustable valve group (44%) and shunt underdrainage in the fixed-pressure valve group (25%).

Conclusions

Adjustable shunt valves have decreased the need for shunt revision surgeries due to under- and overdrainage.