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Introduction <p>Selective Nerve Root Block (SNRB) is widely used for managing radicular pain, serving both therapeutic and diagnostic purposes. A complete list of all reported complications associated with SNRB has never been reported.</p> Aim <p>To map the existing evidence on complications associated with lumbar SNRB.</p> Methods <p>A scoping review was conducted of peer-reviewed studies on complications associated with transforaminal or foraminal lumbar SNRB in adults with degenerative spine conditions. A systematic search was performed across six databases on 9th of September 2024. Two independent reviewers screened studies for eligibility.</p> Results <p>Of the 6,939 screened studies, 118 met the inclusion criteria, comprising a total of 15,817 patients and 72,518 SNRB procedures. A total of 145 distinct complication types and 4,439 complications were identified. Of these, 5.2% were classified as mild/moderate and 0.2% as severe according to the CTCAE grading system. The rate of complications for each study varied substantially, ranging from 0.2% to 73% calculated per procedure. Across all studies, the overall adjusted complication rate was 5.4% per procedure and 5.8% per patient. The most frequent were intravascular injection, vasovagal reactions, and central steroid effect. Severe events, including infection and paralysis, were rare (≤ 0.03%).</p> Discussion&#xa0;and conclusion <p>The SNRB procedure has a low complication rate, with serious complications being rare. This scoping review highlights the heterogeneous complication data in publications. Standardized guidelines for SNRB complication reporting are warranted.</p>

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Complications during lumbar selective nerve root block: a scoping review

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年12月20日

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  • Anna Frøbert Welinder,
  • David Kocemba,
  • Viktor Hartmann Kuang,
  • Mikkel Mylius Rasmussen

摘要

Introduction

Selective Nerve Root Block (SNRB) is widely used for managing radicular pain, serving both therapeutic and diagnostic purposes. A complete list of all reported complications associated with SNRB has never been reported.

Aim

To map the existing evidence on complications associated with lumbar SNRB.

Methods

A scoping review was conducted of peer-reviewed studies on complications associated with transforaminal or foraminal lumbar SNRB in adults with degenerative spine conditions. A systematic search was performed across six databases on 9th of September 2024. Two independent reviewers screened studies for eligibility.

Results

Of the 6,939 screened studies, 118 met the inclusion criteria, comprising a total of 15,817 patients and 72,518 SNRB procedures. A total of 145 distinct complication types and 4,439 complications were identified. Of these, 5.2% were classified as mild/moderate and 0.2% as severe according to the CTCAE grading system. The rate of complications for each study varied substantially, ranging from 0.2% to 73% calculated per procedure. Across all studies, the overall adjusted complication rate was 5.4% per procedure and 5.8% per patient. The most frequent were intravascular injection, vasovagal reactions, and central steroid effect. Severe events, including infection and paralysis, were rare (≤ 0.03%).

Discussion and conclusion

The SNRB procedure has a low complication rate, with serious complications being rare. This scoping review highlights the heterogeneous complication data in publications. Standardized guidelines for SNRB complication reporting are warranted.