Background <p>Cryptorchidism represents the most common congenital anomaly of the male urogenital system, affecting 1–4% of term male neonates, with markedly higher incidence rates in preterm infants. Early diagnosis and timely treatment are essential to prevent long-term complications such as infertility and an increased risk of testicular cancer.</p> Objective <p>To provide an overview of current diagnostic and therapeutic strategies for cryptorchidism, with particular emphasis on interdisciplinary aspects in pediatric management.</p> Results <p>Clinical examination remains the cornerstone of diagnosis, supported by ultrasonography and, in selected cases, by laparoscopic assessment. Early orchidopexy within the first year of life is considered as first-line therapy resulting in significantly improved preservation of germ cell and Leydig cell function and a&#xa0;reduced risk of malignant transformation. Hormonal therapy is only applied restrictively in accordance with current guidelines and should not delay surgical treatment. Structured postoperative follow-up into adolescence is essential for the early detection of atrophy, re-ascent, and neoplastic changes.</p> Conclusion <p>Standardized, early, and interdisciplinary management of children with cryptorchidism substantially improves long-term outcomes regarding fertility and oncologic safety. Early surgical intervention remains the key prognostic factor for optimal testicular development and long-term health.</p>

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Interdisziplinäre Prinzipien zur Behandlung von Hodenfehllagen

  • Hannah N. Stundner-Ladenhauf,
  • M. Georgina Brandtner

摘要

Background

Cryptorchidism represents the most common congenital anomaly of the male urogenital system, affecting 1–4% of term male neonates, with markedly higher incidence rates in preterm infants. Early diagnosis and timely treatment are essential to prevent long-term complications such as infertility and an increased risk of testicular cancer.

Objective

To provide an overview of current diagnostic and therapeutic strategies for cryptorchidism, with particular emphasis on interdisciplinary aspects in pediatric management.

Results

Clinical examination remains the cornerstone of diagnosis, supported by ultrasonography and, in selected cases, by laparoscopic assessment. Early orchidopexy within the first year of life is considered as first-line therapy resulting in significantly improved preservation of germ cell and Leydig cell function and a reduced risk of malignant transformation. Hormonal therapy is only applied restrictively in accordance with current guidelines and should not delay surgical treatment. Structured postoperative follow-up into adolescence is essential for the early detection of atrophy, re-ascent, and neoplastic changes.

Conclusion

Standardized, early, and interdisciplinary management of children with cryptorchidism substantially improves long-term outcomes regarding fertility and oncologic safety. Early surgical intervention remains the key prognostic factor for optimal testicular development and long-term health.