Scholarlink

Background <p>Menstrual cycle disorders are a&#xa0;common gynecological problem in adolescents. Increased menstruation (heavy menstrual bleeding, HMB) in the form of hypermenorrhea and menometrorrhagia are a&#xa0;clinical challenge and can significantly impair the quality of life of young women. While most cases are due to physiological immaturity of the hypothalamic–pituitary–ovarian axis, other pathological causes—particularly congenital bleeding disorders—must not be overlooked.</p> Objective <p>This review aims to summarize diagnostic pitfalls and treatment strategies for HMB in adolescents, with a&#xa0;particular emphasis on the recognition and treatment of congenital bleeding disorders and the individualization of therapy to the specific needs of adolescent patients.</p> Methods <p>We have summarized current literature, guideline recommendations, and illustrative clinical cases to provide a&#xa0;structured overview of diagnostic and therapeutic approaches for HMB in adolescents.</p> Results <p>The majority of HMB cases in adolescents are due to anovulatory cycles. Up to 20% of affected adolescents have an underlying bleeding disorder, most commonly von Willebrand disease, thrombocytopenia/thrombopathy, or a&#xa0;bleeding disorder of unknown cause. A&#xa0;careful family and individual bleeding history, supported by targeted laboratory diagnostics, is crucial to identify the cause. Treatment includes supportive measures such as iron supplementation, acute interventions such as high-dose hormone regimens and blood products, as well as long-term options such as combined hormonal contraceptives and hormone-releasing intrauterine devices. Individualized, age-appropriate diagnostic and treatment plans are essential for the quality of life of affected adolescents.</p> Conclusion <p>HMB in adolescents requires a&#xa0;structured diagnostic approach and individualized treatment plans. Increased awareness of the consistent application of guidelines and evidence-based diagnostic and therapeutic measures can improve the quality of life of affected patients.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Menorrhagie in der Adoleszenz

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月18日

查看全文
  • Werner Streif,
  • Jennifer Gebetsberger,
  • Klaus Kapelari,
  • Katharina Winkler-Crepaz

摘要

Background

Menstrual cycle disorders are a common gynecological problem in adolescents. Increased menstruation (heavy menstrual bleeding, HMB) in the form of hypermenorrhea and menometrorrhagia are a clinical challenge and can significantly impair the quality of life of young women. While most cases are due to physiological immaturity of the hypothalamic–pituitary–ovarian axis, other pathological causes—particularly congenital bleeding disorders—must not be overlooked.

Objective

This review aims to summarize diagnostic pitfalls and treatment strategies for HMB in adolescents, with a particular emphasis on the recognition and treatment of congenital bleeding disorders and the individualization of therapy to the specific needs of adolescent patients.

Methods

We have summarized current literature, guideline recommendations, and illustrative clinical cases to provide a structured overview of diagnostic and therapeutic approaches for HMB in adolescents.

Results

The majority of HMB cases in adolescents are due to anovulatory cycles. Up to 20% of affected adolescents have an underlying bleeding disorder, most commonly von Willebrand disease, thrombocytopenia/thrombopathy, or a bleeding disorder of unknown cause. A careful family and individual bleeding history, supported by targeted laboratory diagnostics, is crucial to identify the cause. Treatment includes supportive measures such as iron supplementation, acute interventions such as high-dose hormone regimens and blood products, as well as long-term options such as combined hormonal contraceptives and hormone-releasing intrauterine devices. Individualized, age-appropriate diagnostic and treatment plans are essential for the quality of life of affected adolescents.

Conclusion

HMB in adolescents requires a structured diagnostic approach and individualized treatment plans. Increased awareness of the consistent application of guidelines and evidence-based diagnostic and therapeutic measures can improve the quality of life of affected patients.