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Ampicillin-derived carbon dots as the sensitive probe for the detection of Fe3+ and Cu2+ in living cells and water samples

  • Hongjie Dong,
  • Huanhuan Xie,
  • Xiaoman Xie,
  • Qi Wang,
  • Hang Sun,
  • Wenju Zhu,
  • Guihua Zhao,
  • Chao Xu,
  • Kun Yin,
  • Junmei Zhang

摘要

Water-soluble N-doped fluorescent (FL) carbon dots (ACDs) were successfully fabricated hydrothermally using ampicillin sodium as sole precursor. The produced ACDs exhibit satisfactory optical behavior, favorable photostability, and acceptable water solubility. With bright blue emission at 450 nm, the ACDs were utilized for multivariate sensing Fe3+ and Cu2+ based on the synergistic effect of the inner filter effect (IFE) and static quenching with detection limits of 0.31 μM and 0.26 μM, respectively. The practicality of ACDs has been verified by the successful determination  of Fe3+ and Cu2+ in real water and living cells. These findings confirm the feasibility of the proposed ACDs as FL sensors for efficient and selective detection of Fe3+ and Cu2+, which present promising prospects for real-time monitoring these two metal ions  in environmental and biological systems.

Graphical Abstract