<p>The failure of anti-dip slopes can lead to significant disasters. Low-inclination anti-dip slopes generally have a lower probability of overturning failure or only experience shallow damage, which has led to limited research. However, the presence of weak interlayers can exacerbate slope failure. This study takes the potential source area I (PSA Ⅰ) anti-dip slope in Guang'an Village as a case, investigating the failure of low-inclination anti-dip slopes with weak interlayers, where the rock layer inclination is 50º and the slope angle is 65º, under unloading conditions through physical model experiments. High-speed photography, digital speckle, infrared thermal imaging, and strain gauges were used to monitor dynamic changes in the slope. Results show that the presence of weak interlayers leads to failure in low-inclination anti-dip slopes, with prolonged damage development and different failure types. After unloading, compression of the weak interlayer and bending deformation at the slope toe provide deformation space, causing cracks at the rear of the slope under tensile stress. As excavation continues, cracks propagate and shear slip failure occurs at the slope toe, accelerating failure and causing overturning at the free face, with intensified internal bending deformation. Based on the dynamic characteristics of hard rock layer instability that control slope stability, critical acceleration is incorporated into the slope failure model, providing a new method for evaluating anti-dip slope stability. Long-term monitoring of PSA Ⅰ is crucial due to its potential for catastrophic failure.</p>