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Deceased donor non-composite split liver and intestinal transplantation for children

  • Tatsuya Okamoto,
  • Eri Ogawa,
  • Hideaki Okajima,
  • Yuki Masano,
  • Shinya Okumura,
  • Miki Yamamoto,
  • Elena Yukie Uebayashi,
  • Takenori Suga,
  • Eitaro Hiejima,
  • Shuji Yamamoto,
  • Hironori Haga,
  • Takashi Ito,
  • Etsuro Hatano

摘要

Children with intestinal failure suffer liver damage associated with parenteral nutrition: a condition known as intestinal failure-associated liver disease (IFALD), which requires transplantation of both liver and intestine. In many countries, simultaneous transplantation of these two organs is performed using grafts from a deceased donor, but there have been no such cases in Japan, and the details of the procedure are not clear. Recently, we performed simultaneous split liver and intestinal transplantation in two premature infants with IFALD, using organs from identical deceased donors and achieved good results. These are the first two cases of this procedure being performed in Japan. We report these cases and discuss the important aspects of the surgical and perioperative management.