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Purpose <p>Although rare, primary chest wall sarcomas are complex malignancies necessitating optimal local control and comprehensive treatment. This study aimed to review 9&#xa0;years of cases of primary chest wall sarcomas at a single institution, focusing on their histology, surgical management, and prognosis.</p> Methods <p>A retrospective analysis was performed on 19 patients undergoing chest wall resection for sarcoma from 2012 to 2020. Data on demographics, tumor specifics, resection extent, and adjuvant therapies were collected. Surgical and postoperative outcomes were also assessed.</p> Results <p>The median patient age was 64&#xa0;years. Chondrosarcoma was the most common histology. R0 resection was achieved in all patients, with early postoperative complications occurring in 11% of the patients. Robust chest wall reconstruction was performed, resulting in minimal respiratory complications. The 5-year overall survival and disease-free survival rates were 94% and 68%, respectively. Tumor size and patient age were significant prognostic factors for local recurrence.</p> Conclusion <p>Comprehensive surgical resection, coupled with multidisciplinary preoperative planning, achieves favorable outcomes. Patients aged ≥ 70&#xa0;years and with tumor size ≥ 5&#xa0;cm (<i>P</i> = .047) should be carefully followed up for local recurrence.</p>

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Primary chest wall sarcoma: advances in surgical management and outcomes

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月1日

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  • Shin Tanaka,
  • Eiji Nakata,
  • Tsuyoshi Ryuko,
  • Takuto Itano,
  • Yasuaki Tomioka,
  • Kazuhiko Shien,
  • Ken Suzawa,
  • Kentaroh Miyoshi,
  • Mikio Okazaki,
  • Seiichiro Sugimoto,
  • Toshifumi Ozaki,
  • Shinichi Toyooka

摘要

Purpose

Although rare, primary chest wall sarcomas are complex malignancies necessitating optimal local control and comprehensive treatment. This study aimed to review 9 years of cases of primary chest wall sarcomas at a single institution, focusing on their histology, surgical management, and prognosis.

Methods

A retrospective analysis was performed on 19 patients undergoing chest wall resection for sarcoma from 2012 to 2020. Data on demographics, tumor specifics, resection extent, and adjuvant therapies were collected. Surgical and postoperative outcomes were also assessed.

Results

The median patient age was 64 years. Chondrosarcoma was the most common histology. R0 resection was achieved in all patients, with early postoperative complications occurring in 11% of the patients. Robust chest wall reconstruction was performed, resulting in minimal respiratory complications. The 5-year overall survival and disease-free survival rates were 94% and 68%, respectively. Tumor size and patient age were significant prognostic factors for local recurrence.

Conclusion

Comprehensive surgical resection, coupled with multidisciplinary preoperative planning, achieves favorable outcomes. Patients aged ≥ 70 years and with tumor size ≥ 5 cm (P = .047) should be carefully followed up for local recurrence.