Scholarlink

Purpose <p>The spine is a primary site for metastases; While only 10% of malignant tumors develop symptomatic spinal metastases, these cases significantly impair quality of life. En-Bloc Spondylectomy (EBS) is a rarely employed but potentially curative surgical option for patients with favorable prognoses. This study evaluates the clinical presentation, surgical procedures, outcomes, and complications associated with EBS in patients with spinal metastasis.</p> Methods <p>This retrospective series included 40 consecutive patients who underwent EBS for spinal metastases between June 2010 and October 2021. Clinical characteristics, treatments, complications, recurrence rates, and survival outcomes were analyzed.</p> Results <p>Thoracic spine metastases accounted for 80% of cases. The most common histologies were clear cell carcinoma of the kidney and follicular thyroid tumor. Wide margins were achieved in 38% of cases, marginal in 17%, and intralesional in 45%. The average blood loss was 1665&#xa0;ml, and surgeries averaged 7.5&#xa0;h.Early complications occurred in 32.5% of patients, with neurological deterioration being the most frequent. The 5-year local recurrence-free survival (LRFS) rate was 64.0%, and the 5-year overall survival (OS) rate was 34.5%.</p> Discussion <p>Despite significant technical challenges, EBS offers a viable treatment option for select patients with spinal metastases, particularly in cases of radioresistant histologies. Achieving oncologically adequate margins and careful preoperative planning are crucial for successful outcomes.</p> Conclusion <p>EBS represents a complex but feasible surgical option that may provide durable local control in carefully selected patients with spinal metastases.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

En-Bloc Spondylectomy for spinal metastases: outcomes, indications, and cost analysis in a 40-patient retrospective study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月7日

查看全文
  • Alessandro Luzzati,
  • Stefano Conti,
  • Isabella Sperduti,
  • Simone Mazzoli,
  • Carmela Pizzigallo,
  • Gennaro Scotto,
  • Carmine Zoccali

摘要

Purpose

The spine is a primary site for metastases; While only 10% of malignant tumors develop symptomatic spinal metastases, these cases significantly impair quality of life. En-Bloc Spondylectomy (EBS) is a rarely employed but potentially curative surgical option for patients with favorable prognoses. This study evaluates the clinical presentation, surgical procedures, outcomes, and complications associated with EBS in patients with spinal metastasis.

Methods

This retrospective series included 40 consecutive patients who underwent EBS for spinal metastases between June 2010 and October 2021. Clinical characteristics, treatments, complications, recurrence rates, and survival outcomes were analyzed.

Results

Thoracic spine metastases accounted for 80% of cases. The most common histologies were clear cell carcinoma of the kidney and follicular thyroid tumor. Wide margins were achieved in 38% of cases, marginal in 17%, and intralesional in 45%. The average blood loss was 1665 ml, and surgeries averaged 7.5 h.Early complications occurred in 32.5% of patients, with neurological deterioration being the most frequent. The 5-year local recurrence-free survival (LRFS) rate was 64.0%, and the 5-year overall survival (OS) rate was 34.5%.

Discussion

Despite significant technical challenges, EBS offers a viable treatment option for select patients with spinal metastases, particularly in cases of radioresistant histologies. Achieving oncologically adequate margins and careful preoperative planning are crucial for successful outcomes.

Conclusion

EBS represents a complex but feasible surgical option that may provide durable local control in carefully selected patients with spinal metastases.