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Swiss chiropractic cohort (Swiss ChiCo) pilot study: feasibility for a musculoskeletal cohort study conducted within a nationwide practice-based research network

  • Rahim Lalji,
  • Léonie Hofstetter,
  • Alice Kongsted,
  • Viktor von Wyl,
  • Julia Braun,
  • Milo A. Puhan,
  • Cesar A. Hincapié,
  • Aline Bidlingmeyer,
  • Andreas Fingal,
  • Anja Maire,
  • Antonia Gassner,
  • Astrid Kurmann,
  • Bernhard Pulver,
  • Carole Beetschen,
  • Christian Chervet,
  • Christina Padua,
  • Christof Schmid,
  • Clarisse Noirat-Berdat,
  • Claude Illi,
  • Colette Faas,
  • Corinne R. Minder,
  • Damien Mauron,
  • Dominic Strauss,
  • Elisabeth Fingal,
  • Emilie Léonard,
  • Fabienne Fehr Leu,
  • Federica Gianola,
  • Ilona Salzmann,
  • Jeanne Waldner,
  • Jean-Pierre Cordey,
  • Jérémie Baret,
  • Kirsten Olesen,
  • Laure Béranger,
  • Lea Rohner,
  • Lorene Rabold,
  • Luana Nyirö,
  • Malin Bengtsdotter Thurnherr,
  • Malin Mühlemann,
  • Marcel Arioli,
  • Marielle Hoarau,
  • Marie-Pierre Roy,
  • Martina Uffer,
  • Martine Randoll Schmutz,
  • Martin Merz,
  • Matilde A. Bianchi,
  • Melanie Häusler,
  • Michael Renfer,
  • Michel Aymon,
  • Mireille Schläppi,
  • Nadia Faigaux,
  • Nadia Graf,
  • Nicholas Schenk,
  • Nicole Aeschlimann Kibler,
  • Nicole Schläppi,
  • Nils Osseiran,
  • Nina Yerly,
  • Noemi Amrhein,
  • Patric Beereuter,
  • Patrick Ryser,
  • Peter Bon,
  • Peter Keller,
  • Rebecca Duvanel Austinat,
  • Roland Noirat,
  • Romain Clerc,
  • Roy Bösiger,
  • Samuel Kosewähr,
  • Sarah Filliez,
  • Sara Meier,
  • Serafin Leemann,
  • Seraina Francey,
  • Sibylle Nebiker,
  • Simone Müller,
  • Sonja Nardini,
  • Stephanie Zimmermann,
  • Stefan Rauber,
  • Thierry Schmutz,
  • Thomas Lüthy,
  • Thomas Thurnherr,
  • Tom Leleu,
  • Urs Zahner,
  • Vincent Billa,
  • William Jardine

摘要

Purpose

Practice-based research networks are collaborations between clinicians and researchers to advance primary care research. This study aims to assess the feasibility for longitudinal data collection within a newly established chiropractic PBRN in Switzerland.

Methods

A prospective observational cohort feasibility study was performed. PBRN participating chiropractors were asked to recruit patients seeking new conservative health care for musculoskeletal pain from March 28, 2022, to September 28, 2022. Participants completed clinically oriented survey questions and patient-reported outcome measures before the initial chiropractic assessment as well as 1 h, 2 weeks, 6 weeks, and 12 weeks thereafter. Feasibility was assessed through a variety of process, resource, and management metrics. Patient clinical outcomes were also assessed.

Results

A total of 76 clinicians from 35 unique primary care chiropractic clinics across Switzerland participated. A total of 1431 patients were invited to participate, of which 573 (mean age 47 years, 51% female) were enrolled. Patient survey response proportions were 76%, 64%, 61%, and 56%, at the 1-h, 2-, 6-, and 12-week survey follow-ups, respectively. Evidence of an association was found between increased patient age (OR = 1.03, 95%CI 1.01–1.04), patient from a German-speaking region (OR = 1.81, 95%CI 1.17–2.86), non-smokers (OR = 1.89, 95%CI 1.13–3.17), and increased pain impact score at baseline (OR = 1.18, 95%CI 1.01–1.38) and response to all surveys.

Conclusion

The Swiss ChiCo pilot study exceeded its prespecified feasibility objectives. Nationwide longitudinal data capture was highly feasible. Similar to other practice-based cohorts, participant retention remains a challenge.

Trial registration Swiss chiropractic cohort (Swiss ChiCo) pilot study (ClinicalTrials.gov identifier: NCT05116020).