<p>Lactation is a pivotal physiological phase in Lacaune sheep, which not only supports offspring development but also significantly impacts the metabolic health of the lactating individual. The metabolic demands during lactation induce changes in various metabolic parameters, including liver biomarkers, lipid mobilization, and minerals, which play critical roles in maintaining homeostasis and reflect the overall metabolic state and health of lactating ewes, as well. This study aims to comprehensively determine the effects of lactation on metabolic factors in Lacaune sheep in Kerman. A total of 32 Lacaune ewes comprising 16 lactating ewes and 16 non-lactating ewes with similar age and body weight, to mitigate variability in metabolic responses, were selected for the present study. Blood samples were obtained via jugular venipuncture on 0, 30, 60, and 90 days of lactation. Serum cholesterol (Chol), triglyceride (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT), calcium (Ca), and phosphorus (Ph) were determined by spectrophotometry using standard kits from Parsazmoon Company following the manufacturer’s protocols. The results demonstrated the AST and ALT levels were significantly higher in the lactating group compared to the non-lactating one from day 60 onwards (<i>p </i> &lt;  0.05). Additionally, the lactating group consistently maintained higher ALP values. Significant differences in this enzyme were persistent across the observation period except on day 30 (<i>p </i> &lt;  0.05). Furthermore, TG and Chol levels in the lactating group were higher across all time points, significantly on day 0 for TG and on days 0 and 60 for Chol (<i>p</i>  &lt;  0.05). Moreover, significantly higher phosphorus levels were generally observed in the non-lactating group across the time points, with the exception of day 0. Calcium levels were found to be higher in the non-lactating group than in the lactating group on day 30 onwards (<i>p</i>  &gt;  0.05). This study underscores the significant biochemical modifications experienced by lactating sheep, which highlight the intricate metabolic adjustments required during lactation.</p>

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The effect of lactation on metabolic parameters in Lacaune sheep

  • Mahdi Poursheykhali,
  • Mohammad Mazrouei Sebdani,
  • Amin Ahmadi

摘要

Lactation is a pivotal physiological phase in Lacaune sheep, which not only supports offspring development but also significantly impacts the metabolic health of the lactating individual. The metabolic demands during lactation induce changes in various metabolic parameters, including liver biomarkers, lipid mobilization, and minerals, which play critical roles in maintaining homeostasis and reflect the overall metabolic state and health of lactating ewes, as well. This study aims to comprehensively determine the effects of lactation on metabolic factors in Lacaune sheep in Kerman. A total of 32 Lacaune ewes comprising 16 lactating ewes and 16 non-lactating ewes with similar age and body weight, to mitigate variability in metabolic responses, were selected for the present study. Blood samples were obtained via jugular venipuncture on 0, 30, 60, and 90 days of lactation. Serum cholesterol (Chol), triglyceride (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT), calcium (Ca), and phosphorus (Ph) were determined by spectrophotometry using standard kits from Parsazmoon Company following the manufacturer’s protocols. The results demonstrated the AST and ALT levels were significantly higher in the lactating group compared to the non-lactating one from day 60 onwards (p  <  0.05). Additionally, the lactating group consistently maintained higher ALP values. Significant differences in this enzyme were persistent across the observation period except on day 30 (p  <  0.05). Furthermore, TG and Chol levels in the lactating group were higher across all time points, significantly on day 0 for TG and on days 0 and 60 for Chol (p  <  0.05). Moreover, significantly higher phosphorus levels were generally observed in the non-lactating group across the time points, with the exception of day 0. Calcium levels were found to be higher in the non-lactating group than in the lactating group on day 30 onwards (p  >  0.05). This study underscores the significant biochemical modifications experienced by lactating sheep, which highlight the intricate metabolic adjustments required during lactation.