In this study a novel 2D photonic crystal fiber (PCF) is proposed for the simultaneous detection of blood, breast, cervical, and adrenal gland cancers. The designed sensor contains four channels, which facilitates simultaneous detection of four different cancer cells. To excite the plasmonic effects, a thin layer of Gold (Au) and \(\:{\text{T}\text{a}}_{2}{\text{O}}_{5}\) are coated on the outer side of the cladding layer. Different geometrical parameters are optimized by analysing the confinement loss spectrum using the finite element method (FEM). The simulation outcomes revealed that channel 1 containing blood cancer cells and channel 3 containing adrenal cancer cells support the y-polarization, whereas channel 2 containing the breast cancer sample and channel 4 containing the cervical cancer sample support the x-polarization mode of the electric field. A notable wavelength sensitivity of 5714.286 nm/RIU, 13671.43 nm/RIU, 7857 nm/RIU, and 8333.33 nm/RIU are attained for blood, adrenal gland, breast, and cervical cancer, respectively. Additionally, amplitude sensitivities of 616.92 RIU-1, 407.96 RIU-1, 362.37 RIU-1, and 354.67 RIU-1 are obtained for blood, breast, adrenal, and cervical cancer, respectively. The suggested sensor is capable of potentially identifying four different types of cancer cells simultaneously, making it an ideal choice for the future biomedical industry.
