<p>A novel magnetic-driven drug delivery micropump based on flexible printed circuit board technology is presented in this paper. The proposed micropump consists of a flex PCB (as a diaphragm), two fluidic chambers with two pairs of nozzle-diffuser elements, and two permanent magnets. Two spiral coils are designed on both sides of the flex PCB, which are vertically exposed in a magnetic field due to permanent magnets. Crossing an electric current by coils causes a deflection by the flex PCB diaphragm. That is the base of pumping mechanism. Applying a 1mA rectangular shape electric current to coils is enough to vibrate the flex diaphragm with an amplitude of about 75 µm. That causes a flow rate of about 1.2 nl/s. COMSOL Multiphysics® simulations further reveal that the pump generates a total head of 820 kPa under idealized conditions. The micropump has low power consumption, large-diaphragm displacement, small size, low cost, and the ability to integrate with other possible microfluidic devices. Future work will explore active microvalves to enhance net flow rate and head performance for high-resistance microfluidic applications.</p>

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Design and simulation of a magnetically driven micro-pump based on the flex printed circuit board (FPCB) technique for drug delivery applications

  • Elaheh Asgari,
  • Habib Badri Ghavifekr

摘要

A novel magnetic-driven drug delivery micropump based on flexible printed circuit board technology is presented in this paper. The proposed micropump consists of a flex PCB (as a diaphragm), two fluidic chambers with two pairs of nozzle-diffuser elements, and two permanent magnets. Two spiral coils are designed on both sides of the flex PCB, which are vertically exposed in a magnetic field due to permanent magnets. Crossing an electric current by coils causes a deflection by the flex PCB diaphragm. That is the base of pumping mechanism. Applying a 1mA rectangular shape electric current to coils is enough to vibrate the flex diaphragm with an amplitude of about 75 µm. That causes a flow rate of about 1.2 nl/s. COMSOL Multiphysics® simulations further reveal that the pump generates a total head of 820 kPa under idealized conditions. The micropump has low power consumption, large-diaphragm displacement, small size, low cost, and the ability to integrate with other possible microfluidic devices. Future work will explore active microvalves to enhance net flow rate and head performance for high-resistance microfluidic applications.