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<p>In this paper, a wide-ranging simulation-based study is performed for the first time to compare DM TFET biosensors of SGDG SP-DMTFET, FGDG SP-DMTFET architectures. This research presents an innovative method through the incorporation of a source pocket, which really improves band-to-band tunneling (BTBT) and total biosensor performance. Sensitivity analysis is performed for a wide range of biomolecules with different dielectric constants: Air (K = 1), Streptavidin (K = 2.1), Biotin (K = 2.63), Healthy cell MCF-10&#xa0;A (K = 4.5), Cellulose (K = 6.1), DNA (K = 8.7), and Cancer cell lines MDA-MB-231 (K = 24.5), MCF-7 (K = 27.5), and T47D (K = 32). The outcomes unequivocally show that due to its more efficient gate-to-channel coupling, the FG-DMTFET structure has better drain current sensitivity for all biomolecular interactions than its SG equivalent. This work not only points out the improved electrostatic control provided by FG DG SP-DMTFET but also establishes their new configuration with source pocket engineering as an ultra-sensitive and scalable platform for future-generation label-free biosensing applications.</p>

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Design and optimization analysis through gate engineered DG SP DMTFET for biosensors

  • 期刊论文

  • 发表日期：

    2025年8月9日

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  • P. Harika,
  • Girija Sravani Kondavitee,
  • Srinivasa Rao Karumuri

摘要

In this paper, a wide-ranging simulation-based study is performed for the first time to compare DM TFET biosensors of SGDG SP-DMTFET, FGDG SP-DMTFET architectures. This research presents an innovative method through the incorporation of a source pocket, which really improves band-to-band tunneling (BTBT) and total biosensor performance. Sensitivity analysis is performed for a wide range of biomolecules with different dielectric constants: Air (K = 1), Streptavidin (K = 2.1), Biotin (K = 2.63), Healthy cell MCF-10 A (K = 4.5), Cellulose (K = 6.1), DNA (K = 8.7), and Cancer cell lines MDA-MB-231 (K = 24.5), MCF-7 (K = 27.5), and T47D (K = 32). The outcomes unequivocally show that due to its more efficient gate-to-channel coupling, the FG-DMTFET structure has better drain current sensitivity for all biomolecular interactions than its SG equivalent. This work not only points out the improved electrostatic control provided by FG DG SP-DMTFET but also establishes their new configuration with source pocket engineering as an ultra-sensitive and scalable platform for future-generation label-free biosensing applications.