Modeling and analysis of nanosphere structure for bio-sensing application

Nanosphere structures using noble metals are suitable and efficient for the development of biosensors for the detection of analytes in biological applications based on refractive index-based sensing. The nanosphere structure acts as a surface plasmon device. The gold nanospheres are commonly used as nanodevices. The modeling and analysis of the gold nanosphere structure are carried out in this work. The Mie-scattering algorithm is used to find the extinction efficiency, scattering efficiency, and absorbance efficiency of gold nanospheres, while dipole approximation methods are used as sources in the modeling of gold nanospheres with effective radii. The cross-section efficiency and sensitivity of the nanosphere-based refractive index sensor are analyzed. The mathematical analysis is conducted using the discrete dipole approximation method. The Riccati–Bessel functions are used in the Mie calculations.