In this paper, we are interested in the linear and the nonlinear Rayleigh–Taylor instability for the gravity-driven incompressible Navier–Stokes equations with Navier-slip boundary conditions around a smooth increasing density profile \(\rho _0(x_2)\) in a slab domain \(2\pi L\mathbb T\times (-1,1)\) ( \(L>0\) , \(\mathbb T\) is the usual 1D torus). The linear instability study of the viscous Rayleigh–Taylor model amounts to the study of the following ordinary differential equation on the finite interval \((-1,1)\) , 0.1 \(\begin{aligned} -\lambda ^2 [ \rho _0 k^2 \phi - (\rho _0 \phi ')'] = \lambda \mu (\phi ^{(4)} - 2k^2 \phi '' + k^4 \phi ) - gk^2 \rho _0'\phi , \end{aligned}\) with the boundary conditions 0.2 \(\begin{aligned} {\left\{ \begin{array}{ll} \phi (-1)=\phi (1)=0,\\ \mu \phi ''(1) = \xi _+ \phi '(1), \\ \mu \phi ''(-1) =- \xi _- \phi '(-1), \end{array}\right. } \end{aligned}\) where \(\lambda >0\) is the growth rate in time, \(g>0\) is the gravity constant, k is the wave number and two Navier-slip coefficients \(\xi _{\pm }\) are nonnegative constants. For each \(k\in L^{-1}\mathbb Z{\setminus }\{0\}\) , we define a k-supercritical regime of viscosity coefficient, i.e. \(\mu >\mu _c(k,\Xi )\) with \(\Xi =(\xi _+,\xi _-)\) to describe a spectral analysis by adapting an operator method of Lafitte and Nguyễn (Water Waves 4:259–305, 2022) and to prove that there are infinite nontrivial solutions \((\lambda _n, \phi _n)_{n\ge 1} \) of (0.1)–(0.2) with \(\lambda _n \rightarrow 0\) as \(n\rightarrow \infty \) and \(\phi _n\in H^4((-1,1))\) . Hence, we prove the linear Rayleigh–Taylor instability for any viscosity coefficient \(\mu >0\) . As a by-product, based on the existence of infinitely many normal modes of the linearized problem, we construct a wide class of initial data to the nonlinear equations, being inspired by the previous framework of Guo–Strauss (Commun Pure Appl Math 48:861–894, 1995) and of Grenier (Commun Pure Appl Math 53:1067–1091, 2000) with a refinement, to prove the nonlinear Rayleigh–Taylor instability in a high regime of viscosity coefficient, namely \(\mu >3\sup _{k\in L^{-1}\mathbb Z{\setminus }\{0\}}\mu _c(k,\Xi )\) .