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Purpose <p>This study aimed to evaluate the level of financial toxicity (FT) among caregivers of patients with advanced cancer, identify key influencing factors, and examine whether benefit finding (BF) mediates the relationship between family resilience (FR) and FT.</p> Methods <p>A cross-sectional study was conducted from December 2024 to June 2025 in four public hospitals in Henan province, central China. A total of 286 informal caregivers of patients with advanced cancer completed the General Information Questionnaire, the Financial Toxicity Scale for Cancer Family Caregivers, the Family Resilience Questionnaire, and the Benefit Finding Scale. Data were analyzed using SPSS 26.0 and AMOS 24.0.</p> Results <p>The mean FT score among caregivers was 57.3 ± 11.6. Multiple linear regression analysis identified several significant factors of FT, including household disposable savings, tumor metastasis, caregiving alone, place of residence, relationship to the patient, FR, and BF (all <i>P</i> &lt; 0.05). BF partially mediated the association between FR and FT, accounting for 28.4% of the total effect.</p> Conclusion <p>Primary caregivers of patients with advanced cancer experience substantial FT. Targeted interventions should prioritize caregivers at higher risk—those with limited savings, caring for patients with distant metastasis, providing care alone, living in rural areas, or being the patient’s spouse. Beyond demographic and clinical factors, both FR and BF serve as protective resources, offering new insights for designing strategies to alleviate FT among cancer caregivers.</p>

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The influence of family resilience and benefit finding on the financial toxicity of primary caregivers of patients with advanced cancer: a cross-sectional study

  • 期刊论文

  • 发表日期：

    2026年7月21日

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  • Yan Dou,
  • Shengjie Guo,
  • Yurong Liu,
  • Yawan Lu,
  • Weizhen Liu,
  • Panpan Cui

摘要

Purpose

This study aimed to evaluate the level of financial toxicity (FT) among caregivers of patients with advanced cancer, identify key influencing factors, and examine whether benefit finding (BF) mediates the relationship between family resilience (FR) and FT.

Methods

A cross-sectional study was conducted from December 2024 to June 2025 in four public hospitals in Henan province, central China. A total of 286 informal caregivers of patients with advanced cancer completed the General Information Questionnaire, the Financial Toxicity Scale for Cancer Family Caregivers, the Family Resilience Questionnaire, and the Benefit Finding Scale. Data were analyzed using SPSS 26.0 and AMOS 24.0.

Results

The mean FT score among caregivers was 57.3 ± 11.6. Multiple linear regression analysis identified several significant factors of FT, including household disposable savings, tumor metastasis, caregiving alone, place of residence, relationship to the patient, FR, and BF (all P < 0.05). BF partially mediated the association between FR and FT, accounting for 28.4% of the total effect.

Conclusion

Primary caregivers of patients with advanced cancer experience substantial FT. Targeted interventions should prioritize caregivers at higher risk—those with limited savings, caring for patients with distant metastasis, providing care alone, living in rural areas, or being the patient’s spouse. Beyond demographic and clinical factors, both FR and BF serve as protective resources, offering new insights for designing strategies to alleviate FT among cancer caregivers.