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Objective <p>This study aimed to examine the impact of perceived family support on the life satisfaction of caregivers of patients with hematological malignancies, focusing on the mediating roles of hope and rumination.</p> Methods <p>A cross-sectional survey was conducted among 299 caregivers who were recruited from two tertiary hospitals in China between February 2023 and October 2024. Family support, hope, rumination, and life satisfaction were assessed using the family support subscale of the Multidimensional Scale of Perceived Social Support, the Herth Hope Index, the Ruminative Responses Scale, and the Satisfaction with Life Scale, respectively. Structural equation modeling (SEM) and bootstrapping methods were employed to examine the mediating effects.</p> Results <p>Structural equation modeling revealed that family support was positively associated with caregivers’ life satisfaction (<i>β</i> = 0.23, <i>p</i> &lt; 0.001). Family support was also associated with lower levels of rumination (<i>β</i> =  − 0.28; <i>p</i> &lt; 0.001) and higher levels of hope (<i>β</i> = 0.43; <i>p</i> &lt; 0.001). Rumination was negatively associated with life satisfaction (<i>β</i> =  − 0.31, <i>p</i> &lt; 0.001), whereas hope was positively associated with life satisfaction (<i>β</i> = 0.21, <i>p</i> &lt; 0.01). The results of the mediation analyses further confirmed significant indirect effects via rumination and hope, including a sequential pathway (family support → rumination → hope → life satisfaction).</p> Conclusion <p>These findings suggest that family support enhances caregivers’ life satisfaction not only directly but also indirectly by reducing rumination and fostering hope. Interventions that strengthen family support and target maladaptive rumination while promoting hope may be beneficial for improving the psychological well-being of caregivers of patients with hematological malignancies.</p>

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From rumination quagmire to hope’s flame: a cross-sectional mediation study of family support and life satisfaction among hematological cancer caregivers

  • 期刊论文

  • 发表日期：

    2026年4月24日

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  • Shiyou Fu,
  • Xibin Xiao,
  • Zhengjia Ren

摘要

Objective

This study aimed to examine the impact of perceived family support on the life satisfaction of caregivers of patients with hematological malignancies, focusing on the mediating roles of hope and rumination.

Methods

A cross-sectional survey was conducted among 299 caregivers who were recruited from two tertiary hospitals in China between February 2023 and October 2024. Family support, hope, rumination, and life satisfaction were assessed using the family support subscale of the Multidimensional Scale of Perceived Social Support, the Herth Hope Index, the Ruminative Responses Scale, and the Satisfaction with Life Scale, respectively. Structural equation modeling (SEM) and bootstrapping methods were employed to examine the mediating effects.

Results

Structural equation modeling revealed that family support was positively associated with caregivers’ life satisfaction (β = 0.23, p < 0.001). Family support was also associated with lower levels of rumination (β =  − 0.28; p < 0.001) and higher levels of hope (β = 0.43; p < 0.001). Rumination was negatively associated with life satisfaction (β =  − 0.31, p < 0.001), whereas hope was positively associated with life satisfaction (β = 0.21, p < 0.01). The results of the mediation analyses further confirmed significant indirect effects via rumination and hope, including a sequential pathway (family support → rumination → hope → life satisfaction).

Conclusion

These findings suggest that family support enhances caregivers’ life satisfaction not only directly but also indirectly by reducing rumination and fostering hope. Interventions that strengthen family support and target maladaptive rumination while promoting hope may be beneficial for improving the psychological well-being of caregivers of patients with hematological malignancies.