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<p>Physical training is one of the noninvasive cornerstones of symptomatic treatment for knee osteoarthritis recognized by many medical societies; however, there are also patients who do not benefit from it or whose condition worsens. In recent years, quantitative sensory testing (QST) has come into focus as a&#xa0;prognostic factor for determining the best treatment method for each individual. In the present study, the pressure pain threshold and the conditioned pressure pain modulation were measured before and after an 8‑week training intervention in 72&#xa0;patients (43&#xa0;women, 29&#xa0;men; age: 61.7 ± 8.9&#xa0;years, height 172 ± 9.7 cm, weight: 93.2 ± 19.3 kg, body mass index, BMI: 31.5 + 6.2 kg × m<sup>-2</sup>) with painful knee osteoarthritis. The disease-specific Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire and the Depression Anxiety Stress Scale (DASS) were also used before and after the intervention. Neither the QST parameter results measured before the intervention nor the DASS data had any prognostic relevance for changes in pain symptoms, coping with activities of daily life or quality of life.</p>

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Prognostischer Wert von Druckschmerzschwellen für den therapeutischen Erfolg eines Kraft-Ausdauer-Trainings bei Patienten mit Kniearthrose

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月27日

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  • Klaus Baum,
  • Bianca Holsten,
  • Michael Häfner,
  • Martina Schaper-Hörning,
  • Stefan Taube,
  • Anja Terjung

摘要

Physical training is one of the noninvasive cornerstones of symptomatic treatment for knee osteoarthritis recognized by many medical societies; however, there are also patients who do not benefit from it or whose condition worsens. In recent years, quantitative sensory testing (QST) has come into focus as a prognostic factor for determining the best treatment method for each individual. In the present study, the pressure pain threshold and the conditioned pressure pain modulation were measured before and after an 8‑week training intervention in 72 patients (43 women, 29 men; age: 61.7 ± 8.9 years, height 172 ± 9.7 cm, weight: 93.2 ± 19.3 kg, body mass index, BMI: 31.5 + 6.2 kg × m-2) with painful knee osteoarthritis. The disease-specific Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire and the Depression Anxiety Stress Scale (DASS) were also used before and after the intervention. Neither the QST parameter results measured before the intervention nor the DASS data had any prognostic relevance for changes in pain symptoms, coping with activities of daily life or quality of life.