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<p>Opioids are essential for analgesia and part of a&#xa0;multifarious group of drugs. The study of the endogenous opioid system and its receptors contributes to a&#xa0;better understanding of the advantages and disadvantages of opioids and to develop possibilities for optimization of new substances. Interactions with the different opioid receptors and the non-opioid effects are important aspects that increasingly need to be considered in the treatment design to ensure safe and effective pain management.</p>

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Klinische Pharmakologie von Opioidanalgetika

  • 期刊论文

  • 发表日期：

    2025年4月9日

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  • Constanze Rémi,
  • Jennifer Berner,
  • Aleksandra Dukic-Ott,
  • Christina Hepperle

摘要

Opioids are essential for analgesia and part of a multifarious group of drugs. The study of the endogenous opioid system and its receptors contributes to a better understanding of the advantages and disadvantages of opioids and to develop possibilities for optimization of new substances. Interactions with the different opioid receptors and the non-opioid effects are important aspects that increasingly need to be considered in the treatment design to ensure safe and effective pain management.