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<p>Failure to thrive (FTT) is a common clinical concern in pediatric patients with tubulopathies. Defective tubular handling of solutes,&#xa0;electrolytes, and acid–base balance contributes to impaired growth through both renal and systemic mechanisms.&#xa0;This educational review summarizes current evidence on the pathophysiological mechanisms, clinical presentation and management&#xa0;of FTT in pediatric tubulopathies.</p> Graphical abstract <p></p>

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Failure to thrive in children with tubulopathies

  • 期刊论文

  • 发表日期：

    2025年11月20日

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  • Giulio Rivetti,
  • Francesco Emma,
  • Faidra Veligratli,
  • Pierluigi Marzuillo,
  • Detlef Böckenhauer

摘要

Failure to thrive (FTT) is a common clinical concern in pediatric patients with tubulopathies. Defective tubular handling of solutes, electrolytes, and acid–base balance contributes to impaired growth through both renal and systemic mechanisms. This educational review summarizes current evidence on the pathophysiological mechanisms, clinical presentation and management of FTT in pediatric tubulopathies.

Graphical abstract