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Background <p>To determine the influence of obesity on short-term outcomes in patients with blunt liver trauma.</p> Methods <p>The US Nationwide Inpatient Sample (NIS) database 2005–2020 was reviewed to identify patients ≥ 18&#xa0;years old with blunt liver trauma. Patients were categorized based on body mass index (BMI) into morbidly obese (BMI &gt; 40&#xa0;kg/m<sup>2</sup>), obese (30 ≤ BMI ≤ 40&#xa0;kg/m<sup>2</sup>), and non-obese (BMI &lt; 30&#xa0;kg/m<sup>2</sup>) groups.</p> Results <p>A total of 4121 patients were included, representing an estimated 20,382 patients nationwide. The mean age was 46.4&#xa0;years, and 51.0% were male. Both obese and morbidly obese patients had significantly increased risks of in-hospital mortality (obese: adjusted odds ratio [aOR] = 1.59, 95% confidence interval [CI] 1.05–2.14; morbidly obese: aOR = 2.43, 95% CI 1.61–3.65). Morbid obesity was associated with increased risks of acute kidney injury (AKI) (aOR = 1.90, 95% CI 1.50–2.41) and shock (aOR = 1.56, 95% CI 1.21–2.01). However, patients with non-morbid obesity had significantly lower risks of prolonged LOS (aOR = 0.61, 95% CI 0.50–0.75), non-routine discharge (aOR = 0.66, 95% CI 0.53–0.81), and complications (aOR = 0.69, 95% CI: 0.57–0.83) compared to non-obese individuals.</p> Conclusion <p>Patients with morbid obesity who sustain blunt liver trauma are at increased risk of in-hospital mortality, AKI, and shock compared to non-obese individuals. Despite higher mortality risk, non-morbid obese patients have a lower risk of prolonged LOS, non-routine discharges, and complications.</p>

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Obesity and short-term outcomes in blunt liver trauma with and without surgical repair: evidence from the United States Nationwide Inpatient Sample 2005–2020

  • 期刊论文

  • 发表日期：

    2025年9月13日

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  • Sin-Yong Wee,
  • Chi Li,
  • Wei-Ti Su,
  • Shih-Min Ying,
  • Hao-Ping Wang

摘要

Background

To determine the influence of obesity on short-term outcomes in patients with blunt liver trauma.

Methods

The US Nationwide Inpatient Sample (NIS) database 2005–2020 was reviewed to identify patients ≥ 18 years old with blunt liver trauma. Patients were categorized based on body mass index (BMI) into morbidly obese (BMI > 40 kg/m2), obese (30 ≤ BMI ≤ 40 kg/m2), and non-obese (BMI < 30 kg/m2) groups.

Results

A total of 4121 patients were included, representing an estimated 20,382 patients nationwide. The mean age was 46.4 years, and 51.0% were male. Both obese and morbidly obese patients had significantly increased risks of in-hospital mortality (obese: adjusted odds ratio [aOR] = 1.59, 95% confidence interval [CI] 1.05–2.14; morbidly obese: aOR = 2.43, 95% CI 1.61–3.65). Morbid obesity was associated with increased risks of acute kidney injury (AKI) (aOR = 1.90, 95% CI 1.50–2.41) and shock (aOR = 1.56, 95% CI 1.21–2.01). However, patients with non-morbid obesity had significantly lower risks of prolonged LOS (aOR = 0.61, 95% CI 0.50–0.75), non-routine discharge (aOR = 0.66, 95% CI 0.53–0.81), and complications (aOR = 0.69, 95% CI: 0.57–0.83) compared to non-obese individuals.

Conclusion

Patients with morbid obesity who sustain blunt liver trauma are at increased risk of in-hospital mortality, AKI, and shock compared to non-obese individuals. Despite higher mortality risk, non-morbid obese patients have a lower risk of prolonged LOS, non-routine discharges, and complications.