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Introduction <p>Parastomal hernia recurrence is common but poorly defined. We aimed to correlate radiographic recurrence and reoperation for parastomal hernia recurrence with patient-reported outcomes (PROs) to determine the clinical significance of radiographic recurrence and identify potential screening tools.</p> Methods <p>Patient data in the one- and two-year follow-up windows of a registry-embedded randomized controlled trial comparing open retromuscular Sugarbaker and keyhole mesh parastomal hernia repairs (2019–2022) were analyzed. CT scan images were classified using the Moreno-Matias (MM) classification scheme and PROs were analyzed for trends across groups. PROs included stoma-specific quality of life (Colostomy Impact Score – CIS, range 0–38), pain (NIH PROMIS 3a, range 30.7–71.8), abdominal wall-specific quality of life (HerQLes, range 0–100), and the Decision Regret Scale (DRS, range 0–100) in reference to the previous repair.</p> Results <p>Of 150 randomized patients, there were 221 cross-sectional images and 5 reoperations for recurrence with time-matched PROs. Radiographic recurrence classification ordinally correlated with worse stoma-specific quality of life (CIS, <i>p</i> = 0.0001), with a significant difference first noted between MM 0 and MM II (<i>p</i> = 0.02). Reoperation for recurrence was associated with both worse stoma-specific quality of life (CIS, <i>p</i> = 0.02) and pain (PROMIS 3a, <i>p</i> = 0.02). Abdominal wall-specific quality of life and decision-regret were not associated with radiographic recurrence or reoperation.</p> Conclusion <p>Radiographic MM classification appears to be clinically meaningful with regard to stoma-specific quality of life. Significant differences were first observed at MM II, supporting the use of MMII as a cutoff to define a clinically significant parastomal hernia recurrence. Additionally, measurements of stoma-specific quality of life and pain are potential screening mechanisms to identify patients that should have cross-sectional imaging and counseling on reoperation.</p> Graphical Abstract <p></p>

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Characterizing a clinically significant radiographic parastomal hernia recurrence: post hoc analysis of a randomized controlled trial

  • 期刊论文

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  • 发表日期：

    2025年8月11日

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  • William C. Bennett,
  • Sara M. Maskal,
  • Andrew S. Conner,
  • Kimberly P. Woo,
  • Pavel Lenkov,
  • Alvaro C. Carvalho,
  • Daphne Remulla,
  • Ryan C. Ellis,
  • Kimberly S. Miles,
  • Chao Tu,
  • Benjamin T. Miller,
  • Lucas R. Beffa,
  • David M. Krpata,
  • Ajita S. Prabhu,
  • Michael J. Rosen,
  • Clayton C. Petro

摘要

Introduction

Parastomal hernia recurrence is common but poorly defined. We aimed to correlate radiographic recurrence and reoperation for parastomal hernia recurrence with patient-reported outcomes (PROs) to determine the clinical significance of radiographic recurrence and identify potential screening tools.

Methods

Patient data in the one- and two-year follow-up windows of a registry-embedded randomized controlled trial comparing open retromuscular Sugarbaker and keyhole mesh parastomal hernia repairs (2019–2022) were analyzed. CT scan images were classified using the Moreno-Matias (MM) classification scheme and PROs were analyzed for trends across groups. PROs included stoma-specific quality of life (Colostomy Impact Score – CIS, range 0–38), pain (NIH PROMIS 3a, range 30.7–71.8), abdominal wall-specific quality of life (HerQLes, range 0–100), and the Decision Regret Scale (DRS, range 0–100) in reference to the previous repair.

Results

Of 150 randomized patients, there were 221 cross-sectional images and 5 reoperations for recurrence with time-matched PROs. Radiographic recurrence classification ordinally correlated with worse stoma-specific quality of life (CIS, p = 0.0001), with a significant difference first noted between MM 0 and MM II (p = 0.02). Reoperation for recurrence was associated with both worse stoma-specific quality of life (CIS, p = 0.02) and pain (PROMIS 3a, p = 0.02). Abdominal wall-specific quality of life and decision-regret were not associated with radiographic recurrence or reoperation.

Conclusion

Radiographic MM classification appears to be clinically meaningful with regard to stoma-specific quality of life. Significant differences were first observed at MM II, supporting the use of MMII as a cutoff to define a clinically significant parastomal hernia recurrence. Additionally, measurements of stoma-specific quality of life and pain are potential screening mechanisms to identify patients that should have cross-sectional imaging and counseling on reoperation.

Graphical Abstract