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Self-expanding metallic stent insertion for malignant bowel obstruction secondary to gynecologic malignancies: a retrospective analysis

  • Eliahu Yonathan Bekhor,
  • Erez Klein,
  • Hila Shmilovich,
  • Gad Marom,
  • Yair Glazer,
  • Genevieve Bouchard-Fortier,
  • Mai Harris,
  • Eran Shlomovitz

摘要

Background

Malignant bowel obstruction (MBO) is a common complication in advanced and recurrent gynecologic malignancies, with limited treatment options and poor prognosis. Self-expanding metallic stent (SEMS) insertion has emerged as an alternative palliative measure, yet data specific to gynecologic malignancies remains scarce.

Methods

A retrospective analysis was conducted on 61 patients with gynecologic malignancies and malignant large bowel obstruction who underwent colorectal stenting between January 2002 and December 2023. Data, including demographics, procedural details, clinical outcomes, and complications, were collected from electronic medical records.

Results

The mean age of patients was 65.7 years, with ovarian cancer being the most common malignancy (77%). “Technical success” of SEMS insertion was achieved in 91.4% of cases, with a “clinical success” rate of 76.7%. Major complications occurred in 2% and 5% of patients at 30- and 90 days post-procedure, respectively. Overall mortality rates were 4% at 30 days and 28% at 90 days.

Conclusion

SEMS for managing MBO is a promising alternative to surgery in patients with advanced or recurrent gynecologic malignancies. It offers high technical and clinical success rates with acceptable complication rates. Further research is needed to delineate optimal patient selection criteria and refine procedural techniques to maximize outcomes in this challenging population.