Scholarlink

<p>Microbial fermentation for succinic acid production has the advantages of a short production cycle, renewable raw materials, and mild reaction conditions, and is recognized as a promising green approach. However, the succinic acid fermentation process is often accompanied by by-products such as formic acid and acetic acid, which increase the cost of subsequent separation and waste resources. This study proposed a green integrated process in which <i>Rhodotorula glutinis</i> As2.703 was used to selectively metabolize formic acid and acetic acid in succinic acid fermentation broth to produce high-value-added single-cell protein (SCP), while succinic acid was retained. The results showed that <i>R. glutinis</i> As2.703 achieved a utilization rate of 100% for formic acid and acetic acid in succinic acid fermentation broth, with a biomass of 7.05&#xa0;g/L and a biomass yield of 0.46&#xa0;g/g. The protein, lipid, and carotenoid contents in SCP were 53.11%, 16.65%, and 194.15&#xa0;µg/g, respectively. SuperPro Designer<sup>®</sup> was used to simulate the process of producing 54,331 tons of succinic acid annually. After integrating the SCP production module, the process achieved an annual output of 11,935 tons of SCP, with an annual revenue of 19.81&#xa0;million USD. The operating cost for the SCP module was only 8.27&#xa0;million USD/year, resulting in a net annual profit of 11.54&#xa0;million USD. This technology not only reduced the separation cost of succinic acid but also provided a high-quality protein source for the feed industry, significantly improving the economic viability and sustainability of succinic acid production.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Selective utilization of formic acid and acetic acid in succinic acid fermentation broth to produce single-cell protein using Rhodotorula glutinis

  • 期刊论文

  • 发表日期：

    2025年11月3日

查看全文
  • Fuqiang Liu,
  • Pengfei Wu,
  • Lin Yu,
  • Zitu Lü,
  • Xinying Sun,
  • Jiaxin Li,
  • Lei Liu,
  • Jing Wu,
  • Jianan Zhang

摘要

Microbial fermentation for succinic acid production has the advantages of a short production cycle, renewable raw materials, and mild reaction conditions, and is recognized as a promising green approach. However, the succinic acid fermentation process is often accompanied by by-products such as formic acid and acetic acid, which increase the cost of subsequent separation and waste resources. This study proposed a green integrated process in which Rhodotorula glutinis As2.703 was used to selectively metabolize formic acid and acetic acid in succinic acid fermentation broth to produce high-value-added single-cell protein (SCP), while succinic acid was retained. The results showed that R. glutinis As2.703 achieved a utilization rate of 100% for formic acid and acetic acid in succinic acid fermentation broth, with a biomass of 7.05 g/L and a biomass yield of 0.46 g/g. The protein, lipid, and carotenoid contents in SCP were 53.11%, 16.65%, and 194.15 µg/g, respectively. SuperPro Designer® was used to simulate the process of producing 54,331 tons of succinic acid annually. After integrating the SCP production module, the process achieved an annual output of 11,935 tons of SCP, with an annual revenue of 19.81 million USD. The operating cost for the SCP module was only 8.27 million USD/year, resulting in a net annual profit of 11.54 million USD. This technology not only reduced the separation cost of succinic acid but also provided a high-quality protein source for the feed industry, significantly improving the economic viability and sustainability of succinic acid production.

Graphical abstract