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<p>We sought to investigate the inter- and intra-country variation in paediatric heart transplantation (HTx) and mechanical circulatory support (MCS) availability and practice in Europe.&#xa0;Data was obtained through a survey circulated to paediatric transplant cardiologists identified through the Association of European Paediatric and Congenital Cardiology between November 2022 and March 2023.&#xa0;Twenty-eight respondents from twenty-eight European countries completed the survey. Twenty-four (86%) had paediatric and 25 (89%) had adult congenital HTx services. National paediatric HTx centre density ranged from 0.00 to 5.35 per 10 million inhabitants. Eighteen (64%) countries followed either Eurotransplant or Scandiatransplant protocols for organ allocation and 59% of the surveyed countries had low HTx volumes (&lt; 4 paediatric HTx annually), based on the self-reported numbers. A ventricular assist device (VAD) programme was operational in 22 (79%) countries. In only 9 countries (38%), there were dedicated resources for HTx as part of the hospital budget; however, a vast majority (77%) reported that families suffered no cost when a VAD was utilised. Twenty-one countries (78%) reported limited intensive care unit beds and 14 (54%) reported that HTx impacted on congenital heart surgery cases. Only 12 of 27 countries (44%) had a standardised national protocol for post-HTx care. There was no correlation between paediatric HTx centre density, population or GDP per capita.</p><p><i>Conclusion</i>:&#xa0;There is a high degree of variation both within and between the surveyed European countries with regard to paediatric HTx centre density, VAD availability, listing protocols, and post-HTx management. Multiple factors contribute to this heterogeneity, which makes standardisation of HTx listing and VAD criteria challenging. Increased cross-national collaborative efforts between European countries may strengthen both HTx and MCS availability and outcomes, especially in regions with several smaller neighbouring countries.<Table Float="No" ID="Taba"> <tgroup cols="2"> <colspec align="left" colname="c1" colnum="1" /> <colspec align="left" colname="c2" colnum="2" /> <tbody> <row> <entry nameend="c2" namest="c1"> <p><b>What is Known:</b></p> <p>•&#xa0;<i>The care of paediatric heart transplant (HTx) and mechanical support (MCS) patients varies across Europe.</i></p> </entry> </row> <row> <entry nameend="c2" namest="c1"> <p><b>What is New:</b></p> <p>•&#xa0;<i>This paper elucidates the differences in transplant service organisation and the care of transplant and MCS patients in twenty-eight European countries.</i></p> <p>•&#xa0;<i>These findings could potentially encourage broader open dialogue and facilitate collaboration across European paediatric HTx centres with development of standardised listing criteria, improved collective European registry data and creation of standards for screening post-HTx patients.</i></p> </entry> </row> </tbody> </tgroup> </Table></p>

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Current availability and status of paediatric cardiac transplantation and mechanical circulatory support in twenty-eight European countries

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月15日

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  • Oscar van der Have,
  • Esme Dunne,
  • Karin Tran-Lundmark,
  • Julie Wacker,
  • Ina Michel-Behnke,
  • Karel Koubsky,
  • Annemarie Krauss,
  • Johan Van Cleemput,
  • Sigurdur Sverrir Stephensen,
  • Michiel Dalinghaus,
  • Dorotea Šijak,
  • Mirko Topalovic,
  • Inguna Lubaua,
  • Zulal Ulger,
  • Vladimiro Vida,
  • Klaus Juul,
  • Christian Balmer,
  • Senka Mesihovic-Dinarevic,
  • José Fragata,
  • Bohdan Maruszewski,
  • Taisto Sarkola,
  • László Ablonczy,
  • Iolanda Muntean,
  • Martin Zahorec,
  • Milind Chaudhari,
  • Thomas Möller,
  • Damien Bonnet,
  • Jacob Simmonds,
  • Zdenka Reinhardt,
  • Colin J. McMahon

摘要

We sought to investigate the inter- and intra-country variation in paediatric heart transplantation (HTx) and mechanical circulatory support (MCS) availability and practice in Europe. Data was obtained through a survey circulated to paediatric transplant cardiologists identified through the Association of European Paediatric and Congenital Cardiology between November 2022 and March 2023. Twenty-eight respondents from twenty-eight European countries completed the survey. Twenty-four (86%) had paediatric and 25 (89%) had adult congenital HTx services. National paediatric HTx centre density ranged from 0.00 to 5.35 per 10 million inhabitants. Eighteen (64%) countries followed either Eurotransplant or Scandiatransplant protocols for organ allocation and 59% of the surveyed countries had low HTx volumes (< 4 paediatric HTx annually), based on the self-reported numbers. A ventricular assist device (VAD) programme was operational in 22 (79%) countries. In only 9 countries (38%), there were dedicated resources for HTx as part of the hospital budget; however, a vast majority (77%) reported that families suffered no cost when a VAD was utilised. Twenty-one countries (78%) reported limited intensive care unit beds and 14 (54%) reported that HTx impacted on congenital heart surgery cases. Only 12 of 27 countries (44%) had a standardised national protocol for post-HTx care. There was no correlation between paediatric HTx centre density, population or GDP per capita.

Conclusion: There is a high degree of variation both within and between the surveyed European countries with regard to paediatric HTx centre density, VAD availability, listing protocols, and post-HTx management. Multiple factors contribute to this heterogeneity, which makes standardisation of HTx listing and VAD criteria challenging. Increased cross-national collaborative efforts between European countries may strengthen both HTx and MCS availability and outcomes, especially in regions with several smaller neighbouring countries.

What is Known:

• The care of paediatric heart transplant (HTx) and mechanical support (MCS) patients varies across Europe.

What is New:

• This paper elucidates the differences in transplant service organisation and the care of transplant and MCS patients in twenty-eight European countries.

• These findings could potentially encourage broader open dialogue and facilitate collaboration across European paediatric HTx centres with development of standardised listing criteria, improved collective European registry data and creation of standards for screening post-HTx patients.