<p>Although exercise is recommended for children with asthma, inconsistencies in study findings limit the development of standardized exercise prescriptions. This study aimed to investigate the effect of karaoke training applied with telerehabilitation-based exercise training on health-related outcomes in children with asthma. Twenty-eight children with asthma were randomly assigned in equal numbers to a study group (SG) or a control group (CG), with 25 completing 24 individualized online exercise sessions over 8&#xa0;weeks. In addition, SG performed singing exercises using a karaoke application. The primary outcome was pulmonary function, with secondary outcomes including perception of dyspnea, perception of fatigue, thoracic expansion, respiratory and peripheral muscle function, functional capacity, asthma control, and quality of life. Both groups showed significant improvements in pulmonary functions, respiratory muscle strength, thoracic expansion, functional capacity, asthma control (ACT), and the Pediatric Asthma Quality of Life Questionnaire scores (PAQLQ) (<i>p</i> &lt; 0.05). However, SG demonstrated significantly greater improvements in peak expiratory flow, maximal expiratory pressure, dyspnea on exertion, thoracic expansion (axillary and subcostal), 1-min sit-to-stand test, ACT, and PAQLQ (activity limitation, symptoms, total scores) compared to CG (<i>p</i> &lt; 0.05).</p><p><i>Conclusion</i>:&#xa0;Telerehabilitation-based exercises have positive effects on health-related outcomes. Adding online karaoke training enhances engagement and increases therapeutic gains in children with asthma</p><p><Table Float="No" ID="Taba"> <tgroup cols="2"> <colspec align="left" colname="c1" colnum="1" /> <colspec align="left" colname="c2" colnum="2" /> <tbody> <row> <entry nameend="c2" namest="c1"> <p><b>What is Known:</b></p> <p>•<i> Ongoing inconsistencies in exercise-related studies prevent consensus on optimal exercise prescription for asthma patients.</i></p> <p>• <i>Singing training has been studied in different research designs and shown beneficial effects in various respiratory diseases, especially COPD</i>.</p> </entry> </row> <row> <entry nameend="c2" namest="c1"> <p><b>What is New:</b></p> <p>• <i>Telerehabilitation-based exercise programs, incorporating breathing and calisthenic exercises, have shown positive effects on health-related outcomes in children with asthma.</i></p> <p>• <i>Karaoke-based singing integrated into online exercise sessions enhances engagement and increases therapeutic gains in children with asthma</i>.</p> </entry> </row> </tbody> </tgroup> </Table></p>