Purpose <p>Understanding physiological determinants of lactate threshold 2 (LT2) is crucial for tracking adaptations and deriving individualized training recommendations in cycling. Therefore, the study investigated: 1. the accuracy of modeling power output at LT2 in young athletes of both sexes using maximal oxygen uptake (<InlineEquation ID="IEq1"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq1.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="54" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> </mrow> </math></EquationSource> </InlineEquation>), fractional utilization of <InlineEquation ID="IEq2"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq1.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="54" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> </mrow> </math></EquationSource> </InlineEquation> (%<InlineEquation ID="IEq3"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq1.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="54" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> </mrow> </math></EquationSource> </InlineEquation>), and oxygen cost of cycling (Cc); 2. the influence of Cc&#xa0;determination on the model accuracy; 3. the influence of the model predictors and inclusion of maximal lactate accumulation rate (<InlineEquation ID="IEq4"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq4.gif" Format="GIF" Height="16" Rendition="HTML" Resolution="72" Type="Linedraw" Width="51" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{c}}La_\textrm{max}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>c</mi> <mo>˙</mo> </mover> <mi>L</mi> <msub> <mi>a</mi> <mtext>max</mtext> </msub> </mrow> </math></EquationSource> </InlineEquation>) on power at LT2 depending on sex.</p> Methods <p>Eighty-three cyclists and triathletes (22 females, 61 males; age [median&#xa0;and IQR]: 14.6 [13.8–17.6] years, <InlineEquation ID="IEq6"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq1.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="54" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> </mrow> </math></EquationSource> </InlineEquation> [mean ± SD]: 59.2 ± 6.5 mL⋅kg<sup>–1</sup>⋅min<sup>–1</sup>) performed&#xa0;an incremental test to determine power at LT2, <InlineEquation ID="IEq8"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq8.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="60" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}},\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> <mo>,</mo> </mrow> </math></EquationSource> </InlineEquation> %<InlineEquation ID="IEq9"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq1.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="54" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> </mrow> </math></EquationSource> </InlineEquation> at LT2, and Cc&#xa0;(assessed at 3 W⋅kg<sup>–1</sup>, 75% <InlineEquation ID="IEq10"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq8.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="60" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}},\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> <mo>,</mo> </mrow> </math></EquationSource> </InlineEquation> and 90% LT2).</p> Results <p>Modeled and experimentally determined power at LT2 demonstrated excellent agreement for all, male and female athletes (ICC <InlineEquation ID="IEq11"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq11.gif" Format="GIF" Height="15" Rendition="HTML" Resolution="72" Type="Linedraw" Width="19" /> </InlineMediaObject> <EquationSource Format="TEX">\(\ge\)</EquationSource> <EquationSource Format="MATHML"><math> <mo>≥</mo> </math></EquationSource> </InlineEquation> 0.961), with Cc at 90% LT2 providing the highest accuracy (ICC <InlineEquation ID="IEq12"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq11.gif" Format="GIF" Height="15" Rendition="HTML" Resolution="72" Type="Linedraw" Width="19" /> </InlineMediaObject> <EquationSource Format="TEX">\(\ge\)</EquationSource> <EquationSource Format="MATHML"><math> <mo>≥</mo> </math></EquationSource> </InlineEquation> 0.986). The three physiological determinants explained <InlineEquation ID="IEq13"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq11.gif" Format="GIF" Height="15" Rendition="HTML" Resolution="72" Type="Linedraw" Width="19" /> </InlineMediaObject> <EquationSource Format="TEX">\(\ge\)</EquationSource> <EquationSource Format="MATHML"><math> <mo>≥</mo> </math></EquationSource> </InlineEquation> 98% of the variance in power at LT2, with the largest unique contribution from <InlineEquation ID="IEq14"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq1.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="54" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> </mrow> </math></EquationSource> </InlineEquation> (62 and 67% of total <InlineEquation ID="IEq15"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq15.gif" Format="GIF" Height="16" Rendition="HTML" Resolution="72" Type="Linedraw" Width="21" /> </InlineMediaObject> <EquationSource Format="TEX">\(R^2\)</EquationSource> <EquationSource Format="MATHML"><math> <msup> <mi>R</mi> <mn>2</mn> </msup> </math></EquationSource> </InlineEquation>), followed by Cc&#xa0;(8 and 34%) and %<InlineEquation ID="IEq16"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq1.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="54" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> </mrow> </math></EquationSource> </InlineEquation> at LT2 (5 and 12%) in males and females, respectively, while <InlineEquation ID="IEq17"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq4.gif" Format="GIF" Height="16" Rendition="HTML" Resolution="72" Type="Linedraw" Width="51" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{c}}La_\textrm{max}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>c</mi> <mo>˙</mo> </mover> <mi>L</mi> <msub> <mi>a</mi> <mtext>max</mtext> </msub> </mrow> </math></EquationSource> </InlineEquation> did not improve the regression.</p> Conclusion <p><InlineEquation ID="IEq18"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq18.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="60" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}, \)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> <mo>,</mo> </mrow> </math></EquationSource> </InlineEquation> %<InlineEquation ID="IEq19"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq1.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="54" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> </mrow> </math></EquationSource> </InlineEquation> at LT2 and Cc&#xa0;accurately predict power at LT2 in young cycling athletes independent of sex, with determination of Cc&#xa0;at 90% LT2 providing the highest accuracy. While <InlineEquation ID="IEq20"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="421_2025_5744_Article_IEq1.gif" Format="GIF" Height="25" Rendition="HTML" Resolution="72" Type="Linedraw" Width="54" /> </InlineMediaObject> <EquationSource Format="TEX">\({\dot{V}}\textrm{O}_{2_\textrm{peak}}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mover accent="true"> <mi>V</mi> <mo>˙</mo> </mover> <msub> <mtext>O</mtext> <msub> <mn>2</mn> <mtext>peak</mtext> </msub> </msub> </mrow> </math></EquationSource> </InlineEquation> contributes most to LT2 in both sexes, Cc appears more important in young females.</p>

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Modeling lactate threshold in cycling—influence of sex, maximal oxygen uptake, and cost of cycling in young athletes

  • Jonas Fischer,
  • Finn Hävecker,
  • Sanghyeon Ji,
  • Patrick Wahl,
  • Sebastian Keller

摘要

Purpose

Understanding physiological determinants of lactate threshold 2 (LT2) is crucial for tracking adaptations and deriving individualized training recommendations in cycling. Therefore, the study investigated: 1. the accuracy of modeling power output at LT2 in young athletes of both sexes using maximal oxygen uptake ( \({\dot{V}}\textrm{O}_{2_\textrm{peak}}\) V ˙ O 2 peak ), fractional utilization of \({\dot{V}}\textrm{O}_{2_\textrm{peak}}\) V ˙ O 2 peak (% \({\dot{V}}\textrm{O}_{2_\textrm{peak}}\) V ˙ O 2 peak ), and oxygen cost of cycling (Cc); 2. the influence of Cc determination on the model accuracy; 3. the influence of the model predictors and inclusion of maximal lactate accumulation rate ( \({\dot{c}}La_\textrm{max}\) c ˙ L a max ) on power at LT2 depending on sex.

Methods

Eighty-three cyclists and triathletes (22 females, 61 males; age [median and IQR]: 14.6 [13.8–17.6] years, \({\dot{V}}\textrm{O}_{2_\textrm{peak}}\) V ˙ O 2 peak [mean ± SD]: 59.2 ± 6.5 mL⋅kg–1⋅min–1) performed an incremental test to determine power at LT2, \({\dot{V}}\textrm{O}_{2_\textrm{peak}},\) V ˙ O 2 peak , % \({\dot{V}}\textrm{O}_{2_\textrm{peak}}\) V ˙ O 2 peak at LT2, and Cc (assessed at 3 W⋅kg–1, 75% \({\dot{V}}\textrm{O}_{2_\textrm{peak}},\) V ˙ O 2 peak , and 90% LT2).

Results

Modeled and experimentally determined power at LT2 demonstrated excellent agreement for all, male and female athletes (ICC \(\ge\) 0.961), with Cc at 90% LT2 providing the highest accuracy (ICC \(\ge\) 0.986). The three physiological determinants explained \(\ge\) 98% of the variance in power at LT2, with the largest unique contribution from \({\dot{V}}\textrm{O}_{2_\textrm{peak}}\) V ˙ O 2 peak (62 and 67% of total \(R^2\) R 2 ), followed by Cc (8 and 34%) and % \({\dot{V}}\textrm{O}_{2_\textrm{peak}}\) V ˙ O 2 peak at LT2 (5 and 12%) in males and females, respectively, while \({\dot{c}}La_\textrm{max}\) c ˙ L a max did not improve the regression.

Conclusion

\({\dot{V}}\textrm{O}_{2_\textrm{peak}}, \) V ˙ O 2 peak , % \({\dot{V}}\textrm{O}_{2_\textrm{peak}}\) V ˙ O 2 peak at LT2 and Cc accurately predict power at LT2 in young cycling athletes independent of sex, with determination of Cc at 90% LT2 providing the highest accuracy. While \({\dot{V}}\textrm{O}_{2_\textrm{peak}}\) V ˙ O 2 peak contributes most to LT2 in both sexes, Cc appears more important in young females.