Purpose <p>To develop and test a formula for contact lens calculation in aphakic infants. This formula, termed the “aphakic Contact Lens” (aCL) formula, utilizes preoperative axial length and keratometry data.</p> Methods <p>This retrospective, consecutive, two-center study used data derived from a development cohort (Freiburg, Germany) to create and optimize the aCL formula in aphakic eyes. A separate validation cohort (Frankfurt, Germany) was used to validate its predictive performance. The accuracy of the aCL formula was compared against: retinoscopy, a previously reported formula (Trivedi and Wilson, TW), and the use of a + 32.0 diopter (D) CL. Performance was evaluated using the prediction error (PE), absolute prediction error (AE) and the number of eyes within a certain range from retinoscopy (± 0.5D, ± 1.0D, ± 2.0D).</p> Results <p>The aCL formula demonstrated comparable absolute prediction errors to retinoscopy (median AE 0.53D vs. 0.69D) and outperforms the TW formula or + 32D CL (median AE 3.25D and 2.63D). The number of eyes within ± 0.5D (38.3%) is lower compared to retinoscopy (50.0%), but comparable for ± 1.0D and better for ± 2.0D (61.7% vs. 66.7%, 83.3% vs. 72.2%). Both perform better than TW formula and + 32.0D (ranging from 0.0% for ± 0.5D to 33.3% for ± 2.0D).</p> Conclusions <p>The aCL formula is a reliable and accurate tool for determining CL power in aphakic infants. It performed superior to other formula-based and default strategies and is comparable to a retinoscopy. Still, follow-up studies with larger cohorts are needed to validate this outcome.</p>

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Correction of aphakia using biometry-based contact lens calculation in pediatric cataract extraction: introducing the aphakic contact lens formula

  • Christoph Lwowski,
  • Klemens Paul Kaiser,
  • Yaroslava Wenner,
  • Navid Farassat,
  • Thomas Kohnen,
  • Wolf A. Lagrèze

摘要

Purpose

To develop and test a formula for contact lens calculation in aphakic infants. This formula, termed the “aphakic Contact Lens” (aCL) formula, utilizes preoperative axial length and keratometry data.

Methods

This retrospective, consecutive, two-center study used data derived from a development cohort (Freiburg, Germany) to create and optimize the aCL formula in aphakic eyes. A separate validation cohort (Frankfurt, Germany) was used to validate its predictive performance. The accuracy of the aCL formula was compared against: retinoscopy, a previously reported formula (Trivedi and Wilson, TW), and the use of a + 32.0 diopter (D) CL. Performance was evaluated using the prediction error (PE), absolute prediction error (AE) and the number of eyes within a certain range from retinoscopy (± 0.5D, ± 1.0D, ± 2.0D).

Results

The aCL formula demonstrated comparable absolute prediction errors to retinoscopy (median AE 0.53D vs. 0.69D) and outperforms the TW formula or + 32D CL (median AE 3.25D and 2.63D). The number of eyes within ± 0.5D (38.3%) is lower compared to retinoscopy (50.0%), but comparable for ± 1.0D and better for ± 2.0D (61.7% vs. 66.7%, 83.3% vs. 72.2%). Both perform better than TW formula and + 32.0D (ranging from 0.0% for ± 0.5D to 33.3% for ± 2.0D).

Conclusions

The aCL formula is a reliable and accurate tool for determining CL power in aphakic infants. It performed superior to other formula-based and default strategies and is comparable to a retinoscopy. Still, follow-up studies with larger cohorts are needed to validate this outcome.