Scholarlink

Purpose <p>Posterior scleritis is an uncommon and difficult to diagnose vision-threatening inflammatory condition, particularly in myopic eyes. This study describes enhanced depth imaging optical coherence tomography (EDI-OCT) features of posterior scleritis in myopic eyes and evaluates the diagnostic value of sub-Tenon’s fluid on EDI-OCT.</p> Methods <p>Retrospective single-centre case series at tertiary eye unit, Moorfields Eye Hospital, UK. Ten myopic eyes of nine patients (spherical refractive error ≤ − 1.00D) diagnosed with posterior scleritis between January 2018 and December 2024 included. Demographics, best-corrected visual acuity (BCVA), clinical features, treatment, and outcomes were recorded. Macular EDI-OCT scans were reviewed for inflammatory changes, including sub-Tenon’s fluid, and compared with ultrasound B-scan findings.</p> Results <p>Mean age at presentation was 55 years (range 24–70), 56% female patients and mean refractive error − 4.45D. Mean presenting BCVA was 6/12, improving to 6/9 after treatment (<i>p</i> = 0.009). Presenting symptoms included ocular pain (80% eyes), blurred vision (50%), optic disc swelling sign (40%). All eyes received systemic corticosteroids and 50% required second-line immunosuppression. EDI-OCT demonstrated sub-Tenon’s fluid in 60%, subretinal fluid in 30%, cystoid macular oedema in 20%, and choroidal folds in 40%. Sub-Tenon’s fluid correlated with the ultrasound T-sign (κ = 0.78; 95% CI 0.39–1.00; <i>p</i> = 0.011; 90% agreement). EDI-OCT abnormalities resolved in 80% of eyes at three months. Mean sub-foveal choroidal thickness was 307&#xa0;μm and was not correlated with refractive error.</p> Conclusions <p>Sub-Tenon’s fluid on EDI-OCT may represent a useful biomarker for posterior scleritis in myopic eyes and a non-invasive adjunct for diagnosis and monitoring.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

EDI-OCT detection of sub-Tenon’s fluid in posterior scleritis in myopic eyes: a retrospective case series

  • 期刊论文

  • 发表日期：

    2026年7月11日

查看全文
  • Meera Radia,
  • Shruti Chandra,
  • Meena Arunakirinathan,
  • Harry Petrushkin

摘要

Purpose

Posterior scleritis is an uncommon and difficult to diagnose vision-threatening inflammatory condition, particularly in myopic eyes. This study describes enhanced depth imaging optical coherence tomography (EDI-OCT) features of posterior scleritis in myopic eyes and evaluates the diagnostic value of sub-Tenon’s fluid on EDI-OCT.

Methods

Retrospective single-centre case series at tertiary eye unit, Moorfields Eye Hospital, UK. Ten myopic eyes of nine patients (spherical refractive error ≤ − 1.00D) diagnosed with posterior scleritis between January 2018 and December 2024 included. Demographics, best-corrected visual acuity (BCVA), clinical features, treatment, and outcomes were recorded. Macular EDI-OCT scans were reviewed for inflammatory changes, including sub-Tenon’s fluid, and compared with ultrasound B-scan findings.

Results

Mean age at presentation was 55 years (range 24–70), 56% female patients and mean refractive error − 4.45D. Mean presenting BCVA was 6/12, improving to 6/9 after treatment (p = 0.009). Presenting symptoms included ocular pain (80% eyes), blurred vision (50%), optic disc swelling sign (40%). All eyes received systemic corticosteroids and 50% required second-line immunosuppression. EDI-OCT demonstrated sub-Tenon’s fluid in 60%, subretinal fluid in 30%, cystoid macular oedema in 20%, and choroidal folds in 40%. Sub-Tenon’s fluid correlated with the ultrasound T-sign (κ = 0.78; 95% CI 0.39–1.00; p = 0.011; 90% agreement). EDI-OCT abnormalities resolved in 80% of eyes at three months. Mean sub-foveal choroidal thickness was 307 μm and was not correlated with refractive error.

Conclusions

Sub-Tenon’s fluid on EDI-OCT may represent a useful biomarker for posterior scleritis in myopic eyes and a non-invasive adjunct for diagnosis and monitoring.