Scholarlink

Purpose <p>To analyze choriocapillaris (CC) perfusion using swept-source optical coherence tomography angiography (SS-OCTA) and spectral-domain optical coherence tomography angiography (SD-OCTA) in five CC slabs in patients with intermediate age-related macular degeneration (iAMD).</p> Methods <p>This is a cross-sectional study of 23 eyes of 20 patients who underwent three 3 × 3&#xa0;mm OCTA, one with SS-OCTA and two with SD-OCTA, a non-averaged scan (V1) and a four-scan volume (V4). Percentage of flow deficits (FD%), average size of FD (µm2), total area of FD (mm2) and number of FD were calculated in different CC slabs (automatic, 11–21&#xa0;μm, 21–31&#xa0;μm, 31–41&#xa0;μm, 16–31&#xa0;μm).</p> Results <p>There was a statistically significant difference in all parameters and all slabs analyzed, when comparing SS-OCTA versus SD-OCTA V1 and SD-OCTA V1 versus SD-OCTA V4. Nevertheless, when comparing SS-OCTA versus SD-OCTA V4, significant differences were only found for the automatic and the 31–41&#xa0;μm slab. When comparing the FD% between different slabs on the same device, significant differences were also found.</p> Conclusion <p>Quantification of CC FD% is impacted by the CC slab, the type of OCTA used, and volume averaging in SD-OCTA. Given the significant impact on quantitative results, comparisons between studies and instruments and/or with/without averaging are difficult, even at the same slab depth.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Comparison of choriocapillaris perfusion between swept-source optical coherence tomography angiography and spectral-domain optical coherence tomography angiography in five different choriocapillaris slabs in patients with intermediate age-related macular degeneration

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年6月14日

查看全文
  • Nuria Torrell-Belzach,
  • Eric H. Souied,
  • Hoang Mai Le,
  • Manal Benlahbib,
  • Zoe Dobbels,
  • Ambroisine Erasti Gounfle,
  • Xavier X. Wang,
  • Camille Jung,
  • Alexandra Miere

摘要

Purpose

To analyze choriocapillaris (CC) perfusion using swept-source optical coherence tomography angiography (SS-OCTA) and spectral-domain optical coherence tomography angiography (SD-OCTA) in five CC slabs in patients with intermediate age-related macular degeneration (iAMD).

Methods

This is a cross-sectional study of 23 eyes of 20 patients who underwent three 3 × 3 mm OCTA, one with SS-OCTA and two with SD-OCTA, a non-averaged scan (V1) and a four-scan volume (V4). Percentage of flow deficits (FD%), average size of FD (µm2), total area of FD (mm2) and number of FD were calculated in different CC slabs (automatic, 11–21 μm, 21–31 μm, 31–41 μm, 16–31 μm).

Results

There was a statistically significant difference in all parameters and all slabs analyzed, when comparing SS-OCTA versus SD-OCTA V1 and SD-OCTA V1 versus SD-OCTA V4. Nevertheless, when comparing SS-OCTA versus SD-OCTA V4, significant differences were only found for the automatic and the 31–41 μm slab. When comparing the FD% between different slabs on the same device, significant differences were also found.

Conclusion

Quantification of CC FD% is impacted by the CC slab, the type of OCTA used, and volume averaging in SD-OCTA. Given the significant impact on quantitative results, comparisons between studies and instruments and/or with/without averaging are difficult, even at the same slab depth.