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<p>Multiple sclerosis (MS) is most frequently diagnosed in women between the ages of 20–40, often coinciding with child-rearing years. In this analysis of MS diagnostic delay stratified by parenthood status, women with children had longer time to MS diagnosis than those without children (β = 1.28, <i>p</i> = 0.001), controlling for age at symptom onset, progressive disease subtype, smoking, and social drivers of health. A similar difference between men with and without children was not observed. The association between motherhood and longer time to diagnosis was even more notable in employed (β = 1.94, <i>p</i> = 0.001) and single (β = 1.61, <i>p</i> = 0.001) women.</p>

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Motherhood and diagnostic delay among women with multiple sclerosis

  • 期刊论文

  • 发表日期：

    2025年11月25日

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  • Alexandra Balshi,
  • John P. Dempsey,
  • Sachin Kumbar,
  • Nova Manning,
  • Alexis T. Ford,
  • Ursela Baber,
  • Riley Bove,
  • Jacob A. Sloane

摘要

Multiple sclerosis (MS) is most frequently diagnosed in women between the ages of 20–40, often coinciding with child-rearing years. In this analysis of MS diagnostic delay stratified by parenthood status, women with children had longer time to MS diagnosis than those without children (β = 1.28, p = 0.001), controlling for age at symptom onset, progressive disease subtype, smoking, and social drivers of health. A similar difference between men with and without children was not observed. The association between motherhood and longer time to diagnosis was even more notable in employed (β = 1.94, p = 0.001) and single (β = 1.61, p = 0.001) women.