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Background <p>Chronic pharyngitis (CP) is a prevalent but poorly defined inflammatory disorder of the upper aerodigestive tract. Despite increasing attention, research in this field remains fragmented, with heterogeneous diagnostic criteria and inconsistent therapeutic approaches. To clarify the intellectual landscape and inform research prioritization and hypothesis generation, we conducted the first comprehensive bibliometric analysis of CP research.</p> Methods <p>Publications on CP from 2007 to 2025 were retrieved from the Web of Science Core Collection. After screening, 185 eligible articles were analyzed using VOSviewer, CiteSpace, and the bibliometrix R package. Trends in publication output, citation impact, collaboration networks, and thematic evolution were systematically evaluated.</p> Results <p>Global publication output increased steadily, with a peak in 2021. China contributed the largest number of articles, whereas the United States demonstrated greater citation impact and broader international collaboration. Major research hotspots included laryngopharyngeal reflux, proton pump inhibitors, and chronic cough. In contrast, microbial biofilms, neurogenic inflammation, epithelial barrier dysfunction, and patient-centered outcomes were underexplored.</p> Conclusions <p>This study reveals critical gaps in CP research: lack of standardized diagnostic frameworks, insufficiently powered multicenter clinical trials, and limited international collaboration. Future priorities include harmonizing diagnostic criteria, validating biomarkers, and expanding investigations into microbial and neurogenic mechanisms. Strengthening methodological rigor and fostering global cooperation will be essential to translate bibliometric insights into a more coherent research framework that can guide future clinical and translational research.</p>

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Global research trends and knowledge gaps in chronic pharyngitis: A bibliometric analysis (2007–2025)

  • 期刊论文

  • 发表日期：

    2026年4月23日

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  • Houshu Tu,
  • Menglin Chen,
  • Panpan Zhu,
  • Jing Hong,
  • Ling He

摘要

Background

Chronic pharyngitis (CP) is a prevalent but poorly defined inflammatory disorder of the upper aerodigestive tract. Despite increasing attention, research in this field remains fragmented, with heterogeneous diagnostic criteria and inconsistent therapeutic approaches. To clarify the intellectual landscape and inform research prioritization and hypothesis generation, we conducted the first comprehensive bibliometric analysis of CP research.

Methods

Publications on CP from 2007 to 2025 were retrieved from the Web of Science Core Collection. After screening, 185 eligible articles were analyzed using VOSviewer, CiteSpace, and the bibliometrix R package. Trends in publication output, citation impact, collaboration networks, and thematic evolution were systematically evaluated.

Results

Global publication output increased steadily, with a peak in 2021. China contributed the largest number of articles, whereas the United States demonstrated greater citation impact and broader international collaboration. Major research hotspots included laryngopharyngeal reflux, proton pump inhibitors, and chronic cough. In contrast, microbial biofilms, neurogenic inflammation, epithelial barrier dysfunction, and patient-centered outcomes were underexplored.

Conclusions

This study reveals critical gaps in CP research: lack of standardized diagnostic frameworks, insufficiently powered multicenter clinical trials, and limited international collaboration. Future priorities include harmonizing diagnostic criteria, validating biomarkers, and expanding investigations into microbial and neurogenic mechanisms. Strengthening methodological rigor and fostering global cooperation will be essential to translate bibliometric insights into a more coherent research framework that can guide future clinical and translational research.