Aim <p>To study the efficacy of nasal saline irrigation combined with intranasal corticosteroids in treating Allergic Rhinitis and compare it with intranasal corticosteroids alone.</p> Methodology <p>A prospective, randomized trial conducted at a tertiary care center. Symptomatic individuals diagnosed with Allergic Rhinitis were included. The control group received fluticasone propionate nasal spray (200 mcg/day) and the treatment group received fluticasone propionate nasal spray (200 mcg/day) along with nasal saline irrigation with isotonic normal saline (50 ml/nostril with each irrigation thrice a day). The two groups were followed up for 12 weeks. The outcome was compared using a patient-reported experience measure “Allergic rhinitis scoring system”.</p> Results <p>A total of 120 patients (60 in each group) were included in the study. Pre-intervention, there were no significant differences between the two groups with the Allergic rhinitis scoring system. Post-Intervention, significant improvements were evident across all assessed symptoms: rhinorrhoea (14.93 ± 4.16 vs. 17.80 ± 3.16, p &lt; 0.0001), sneezing (14.40 ± 3.91 vs. 18.27 ± 3.16, p &lt; 0.0001), nasal blockage (10.47 ± 4.66 vs. 13.80 ± 4.80, p = 0.0002), nasal pruritus (17.93 ± 3.17 vs. 19.13 ± 1.96, p = 0.0140), ocular pruritus (18.60 ± 2.84 vs. 19.13 ± 2.22, p = 0.2537), and total Allergic rhinitis scoring system score (77.00 ± 9.79 vs. 88.13 ± 7.70, p &lt; 0.0001).</p> Conclusion <p>Nasal saline irrigation used in conjunction with intranasal corticosteroids more effectively alleviates all symptoms of Allergic rhinitis. However, there was no significant difference in ocular pruritus in both groups.</p> Trial registration <p>Trial registered with Clinical trial registry-India, CTRI/2023/01/048641. URL: <a href="https://ctri.nic.in/Clinicaltrials/main1.php?EncHid=44058.73881">https://ctri.nic.in/Clinicaltrials/main1.php?EncHid=44058.73881</a>.</p>