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<p>Alopecia areata (AA) is a prevalent autoimmune disorder characterized by non-scarring hair loss, affecting individuals of all genders, ages, and races. Despite its prevalence, robust epidemiological data on AA in Asia is lacking. This systematic review aims to assess the prevalence, incidence, economic burden, and quality of life (QoL) impact of AA in the Asian region. A systematic literature review was conducted using PubMed, MEDLINE (OVID), Embase, and Google Scholar to identify relevant studies published between January 2011 and December 2024. The final database search was conducted in December 2024 and included studies from multiple Asian countries. A systematic literature review was conducted using PubMed, MEDLINE (OVID), Embase, and Google Scholar to identify relevant studies published between January 2011 and December 2024. The final database search was conducted in December 2024 and included studies from multiple Asian countries. The findings reveal that AA has a significant psychological impact on patients, contributing to anxiety and depression, and substantially affecting their QoL. The review also highlights the heterogeneity in the clinical presentation of AA, with various subtypes and associated comorbidities such as atopic dermatitis and thyroid disease. The economic burden of AA is considerable, with many patients incurring out-of-pocket expenses for treatment and alternative therapies. Limited evidence shows indirect costs dominate AA’s economic burden for patients and caregivers. This review underscores the need for more focused studies on AA in Asia to better understand its epidemiology and burden, and to improve clinical outcomes through emerging therapies.</p>

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Understanding the epidemiology and burden of Alopecia Areata in Asia: a systematic review

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月18日

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  • Roy Gomez,
  • Etienne Wang Cho Ee

摘要

Alopecia areata (AA) is a prevalent autoimmune disorder characterized by non-scarring hair loss, affecting individuals of all genders, ages, and races. Despite its prevalence, robust epidemiological data on AA in Asia is lacking. This systematic review aims to assess the prevalence, incidence, economic burden, and quality of life (QoL) impact of AA in the Asian region. A systematic literature review was conducted using PubMed, MEDLINE (OVID), Embase, and Google Scholar to identify relevant studies published between January 2011 and December 2024. The final database search was conducted in December 2024 and included studies from multiple Asian countries. A systematic literature review was conducted using PubMed, MEDLINE (OVID), Embase, and Google Scholar to identify relevant studies published between January 2011 and December 2024. The final database search was conducted in December 2024 and included studies from multiple Asian countries. The findings reveal that AA has a significant psychological impact on patients, contributing to anxiety and depression, and substantially affecting their QoL. The review also highlights the heterogeneity in the clinical presentation of AA, with various subtypes and associated comorbidities such as atopic dermatitis and thyroid disease. The economic burden of AA is considerable, with many patients incurring out-of-pocket expenses for treatment and alternative therapies. Limited evidence shows indirect costs dominate AA’s economic burden for patients and caregivers. This review underscores the need for more focused studies on AA in Asia to better understand its epidemiology and burden, and to improve clinical outcomes through emerging therapies.